PMID- 26457587
OWN - NLM
STAT- MEDLINE
DCOM- 20170504
LR  - 20181202
IS  - 1439-7609 (Electronic)
IS  - 1439-7595 (Linking)
VI  - 26
IP  - 4
DP  - 2016 Jul
TI  - A comparison of the ultrasonography images of the joints of patients with 
      rheumatoid arthritis and the corresponding synovial histological findings.
PG  - 534-9
LID - 10.3109/14397595.2015.1106680 [doi]
AB  - OBJECTIVES: The objective of this study is to investigate whether ultrasonography 
      (US) images of joints that underwent surgery reflected the synovial histological 
      findings or clinical indicators and to compare the results of the findings 
      related to large joints (LJs) with those of small joints (SJs). METHODS: The 
      operations were performed on 215 joints in 177 patients with rheumatoid arthritis 
      (RA). The 215 joints included 64 LJs and 151 SJs. The joints with the power 
      Doppler (PD) signal grades 0 and 1 were assigned to group L, while those with 
      grades 2 and 3 were assigned to group H. The Rooney score, Disease Activity 
      Score-erythrocyte sedimentation rate (DAS28), serum matrix metallopeptidase 3 
      (MMP-3), and C-reactive protein (CRP) levels were determined. RESULTS: The Rooney 
      score, DAS28, MMP-3, and CRP levels of the LJs were significantly lower in group 
      L than in group H. In group H, similar results were found in the LJs and SJs, 
      with a significant increase in the disease activity, CRP and MMP-3 levels and the 
      histological findings in comparison to group L. CONCLUSIONS: The PD signal grade 
      was one of the indicators that reflected the degree of synovitis in the 
      histological findings of the active joints of RA patients.
FAU - Abe, Asami
AU  - Abe A
AD  - a Department of Rheumatology , Niigata Rheumatic Center , Niigata , Japan and.
FAU - Ishikawa, Hajime
AU  - Ishikawa H
AD  - a Department of Rheumatology , Niigata Rheumatic Center , Niigata , Japan and.
FAU - Nakazono, Kiyoshi
AU  - Nakazono K
AD  - a Department of Rheumatology , Niigata Rheumatic Center , Niigata , Japan and.
FAU - Murasawa, Akira
AU  - Murasawa A
AD  - a Department of Rheumatology , Niigata Rheumatic Center , Niigata , Japan and.
FAU - Wakaki, Kunihiko
AU  - Wakaki K
AD  - b Department of Pathology , Niigata Prefectural Shibata Hospital , Niigata , 
      Japan.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20151120
PL  - England
TA  - Mod Rheumatol
JT  - Modern rheumatology
JID - 100959226
RN  - 9007-41-4 (C-Reactive Protein)
RN  - EC 3.4.24.17 (Matrix Metalloproteinase 3)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Arthritis, Rheumatoid/blood/*diagnostic imaging/*pathology
MH  - Blood Sedimentation
MH  - C-Reactive Protein/metabolism
MH  - Female
MH  - Humans
MH  - Male
MH  - Matrix Metalloproteinase 3/blood
MH  - Middle Aged
MH  - Severity of Illness Index
MH  - Synovitis/blood/*diagnostic imaging/*pathology
MH  - Ultrasonography, Doppler/*methods
OTO - NOTNLM
OT  - Power Doppler signal
OT  - Rheumatoid arthritis
OT  - Rooney score
OT  - Synovial histological findings
OT  - Ultrasonography
EDAT- 2015/10/13 06:00
MHDA- 2017/05/05 06:00
CRDT- 2015/10/13 06:00
PHST- 2015/10/13 06:00 [entrez]
PHST- 2015/10/13 06:00 [pubmed]
PHST- 2017/05/05 06:00 [medline]
AID - 10.3109/14397595.2015.1106680 [doi]
PST - ppublish
SO  - Mod Rheumatol. 2016 Jul;26(4):534-9. doi: 10.3109/14397595.2015.1106680. Epub 
      2015 Nov 20.