PMID- 26462329 OWN - NLM STAT- MEDLINE DCOM- 20151030 LR - 20191113 IS - 0015-5497 (Print) IS - 0015-5497 (Linking) VI - 63 IP - 3 DP - 2015 TI - Hematological Alterations in Common Carp (Cyprinus carpio L.) Exposed to Herbicides: Pendimethalin and Ethofumesate Tested Separately and in Mixture. PG - 167-74 AB - Herbicides are used in large amounts in agriculture and the evaluation of their toxic effects is of major concern to environmental safety. The aim of the present study was to investigate common carp hematological alterations caused by herbicide exposure. Fish were treated with pendimethalin and ethofumesate tested separately and in mixture administered to aquarium water. Peripheral blood of treated fish was collected after 1, 3 and 7 days of exposure and compared to control. The total number of erythrocytes (RBC), total number of leukocytes (WBC), hematocrit value (Hct), total hemoglobin concentration (Hb), mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC) and leukograms were determined at once. The results indicate that herbicide exposure caused different changes in the hematological profile of the fish. In the case of exposure to individual herbicides, short-term fluctuations of various hematological indices were noted. Moreover, a significant increase in RBC and Hct after a short period of exposure (1-3 days) in fish exposed simultaneously to both tested herbicides was observed. Exposure to herbicides affected the leukocyte profile after 3 and 7 days of duration. Fluctuations of hematological parameters are a typical change in fish exposed to pesticides. FAU - Bojarski, Bartosz AU - Bojarski B FAU - Ludwikowska, Agnieszka AU - Ludwikowska A FAU - Kurek, Anna AU - Kurek A FAU - Pawlak, Krzysztof AU - Pawlak K FAU - Tombarkiewicz, Barbara AU - Tombarkiewicz B FAU - Lutnicka, Hanna AU - Lutnicka H LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Poland TA - Folia Biol (Krakow) JT - Folia biologica JID - 2984758R RN - 0 (Aniline Compounds) RN - 0 (Benzofurans) RN - 0 (Herbicides) RN - 0 (Mesylates) RN - 3051U1Z8KV (ethofumesate) RN - VL6L14C06U (pendimethalin) SB - IM MH - Aniline Compounds/*toxicity MH - Animals MH - Benzofurans/*toxicity MH - Carps MH - *Hematologic Tests MH - Herbicides/*toxicity MH - Mesylates/*toxicity EDAT- 2015/10/16 06:00 MHDA- 2015/10/31 06:00 CRDT- 2015/10/15 06:00 PHST- 2015/10/15 06:00 [entrez] PHST- 2015/10/16 06:00 [pubmed] PHST- 2015/10/31 06:00 [medline] AID - 10.3409/fb63_3.167 [doi] PST - ppublish SO - Folia Biol (Krakow). 2015;63(3):167-74. doi: 10.3409/fb63_3.167.