PMID- 26465891
OWN - NLM
STAT- MEDLINE
DCOM- 20160202
LR  - 20151015
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Linking)
VI  - 56
IP  - 11
DP  - 2015 Oct
TI  - Prediction of Retinal Ischemia in Branch Retinal Vein Occlusion: Spectral-Domain 
      Optical Coherence Tomography Study.
PG  - 6622-9
LID - 10.1167/iovs.15-17678 [doi]
AB  - PURPOSE: To investigate the relationship between spectral-domain optical 
      coherence tomography (SD-OCT) measurements and retinal nonperfusion in patients 
      with branch retinal vein occlusion (BRVO). METHODS: Forty-one patients with BRVO 
      who had recovered from macular edema and had been followed for >/=2 years were 
      included via retrospective, medical record review. Patients were divided into two 
      groups that included 20 nonischemic eyes and 21 ischemic eyes, and 41 fellow 
      control eyes were also included. Using SD-OCT, we measured the thickness of the 
      macular layer, ganglion cell-inner plexiform layer (GC-IPL), and retinal nerve 
      fiber layer (RNFL) in both the BRVO-affected and fellow eyes. The eyes were 
      subdivided into affected and nonaffected areas of BRVO. Each area of normal 
      fellow eyes and BRVO eyes was compared between the two groups. Receiver operating 
      characteristic (ROC) curves were used to evaluate the diagnostic ability of the 
      OCT measurements for ischemic BRVO. RESULTS: The macula, the GC-IPL, and RNFL in 
      the BRVO-affected area were significantly thinner compared to those of the fellow 
      eyes in the two groups. The thickness of macula, GC-IPL, and RNFL in the ischemic 
      BRVO group was also significantly less than in the nonischemic BRVO group. In the 
      ROC curve analysis of a total of 82 eyes, the area under the ROC curve of the 
      RNFL on the ischemic BRVO was the highest at 0.906, followed by the GC-IPL 
      (0.824) and the macula (0.768). CONCLUSIONS: The thickness of macula, GC-IPL, and 
      RNFL in the ischemic BRVO group was significantly reduced compared to the 
      nonischemic BRVO group, especially in the RNFL.
FAU - Lim, Hyung-Bin
AU  - Lim HB
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea.
FAU - Kim, Min-Sun
AU  - Kim MS
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea.
FAU - Jo, Young-Joon
AU  - Jo YJ
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea 2Research Institute for Medical Science, Chungnam 
      National University College of Medicine, Daejeon, Republic of Korea.
FAU - Kim, Jung-Yeul
AU  - Kim JY
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea 2Research Institute for Medical Science, Chungnam 
      National University College of Medicine, Daejeon, Republic of Korea.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - Aged
MH  - Case-Control Studies
MH  - Fluorescein Angiography
MH  - Fundus Oculi
MH  - Humans
MH  - Ischemia/diagnosis/*etiology
MH  - Middle Aged
MH  - Retinal Diseases/diagnosis/*etiology
MH  - Retinal Vein Occlusion/*complications
MH  - Retinal Vessels/*pathology
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence
EDAT- 2015/10/16 06:00
MHDA- 2016/02/03 06:00
CRDT- 2015/10/15 06:00
PHST- 2015/10/15 06:00 [entrez]
PHST- 2015/10/16 06:00 [pubmed]
PHST- 2016/02/03 06:00 [medline]
AID - 2463629 [pii]
AID - 10.1167/iovs.15-17678 [doi]
PST - ppublish
SO  - Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6622-9. doi: 10.1167/iovs.15-17678.