PMID- 26466104
OWN - NLM
STAT- MEDLINE
DCOM- 20160224
LR  - 20151114
IS  - 1532-3145 (Electronic)
IS  - 0363-8715 (Linking)
VI  - 39
IP  - 6
DP  - 2015 Nov-Dec
TI  - Distribution and Clinical Significance of High Signal Intensity of the Myocardium 
      on T2-Weighted Images in 2 Phenotypes of Hypertrophic Cardiomyopathy.
PG  - 951-5
LID - 10.1097/RCT.0000000000000296 [doi]
AB  - OBJECTIVE: The aim of this study was to evaluate distribution and clinical 
      significance of high signal intensity of the myocardium on T2-weighted images 
      (T2-HI) in 2 phenotypes of hypertrophic cardiomyopathy (HCM). METHODS: Thirty-six 
      patients with asymmetrical septal HCM (ASH) and 18 patients with apical HCM (APH) 
      and their 864 myocardial segments were investigated. The distribution of T2-HI 
      was compared with that of late gadolinium enhancement (LGE), and the 
      relationships between T2-HI and clinical risk markers were evaluated. T2 values 
      of the T2-HI were estimated with T2 mapping. RESULTS: The T2-HI was observed in 
      18 segments (3.1%) in 13 patients with ASH (36.1%) and in 12 segments (4.2%) in 8 
      patients with APH (44.4%). It was often localized outside LGE. The presence of 
      T2-HI was related to syncope in ASH (P = 0.016). Furthermore, it had higher T2 
      values (61.1 milliseconds) than the reference myocardium (47.3 milliseconds). 
      CONCLUSIONS: High signal intensity of the myocardium on T2-weighted images often 
      locates outside LGE and reflects myocardial damage, which is related to syncope 
      in ASH.
FAU - Amano, Yasuo
AU  - Amano Y
AD  - From the Departments of *Radiology and daggerCardiology and Intensive Cardiac Care 
      Unit, Nippon Medical School, Tokyo, Japan.
FAU - Aita, Kumiko
AU  - Aita K
FAU - Yamada, Fumi
AU  - Yamada F
FAU - Kitamura, Mitsunobu
AU  - Kitamura M
FAU - Kumita, Shinichiro
AU  - Kumita S
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Comput Assist Tomogr
JT  - Journal of computer assisted tomography
JID - 7703942
RN  - 0 (Contrast Media)
RN  - 0 (Troponin T)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiomyopathy, Hypertrophic/blood/*pathology
MH  - *Contrast Media
MH  - Female
MH  - *Gadolinium DTPA
MH  - Humans
MH  - *Image Enhancement
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Myocardium/*pathology
MH  - Observer Variation
MH  - Phenotype
MH  - Reproducibility of Results
MH  - Retrospective Studies
MH  - Risk
MH  - Syncope
MH  - Troponin T/*blood
EDAT- 2015/10/16 06:00
MHDA- 2016/02/26 06:00
CRDT- 2015/10/15 06:00
PHST- 2015/10/15 06:00 [entrez]
PHST- 2015/10/16 06:00 [pubmed]
PHST- 2016/02/26 06:00 [medline]
AID - 10.1097/RCT.0000000000000296 [doi]
PST - ppublish
SO  - J Comput Assist Tomogr. 2015 Nov-Dec;39(6):951-5. doi: 
      10.1097/RCT.0000000000000296.