PMID- 2646702
OWN - NLM
STAT- MEDLINE
DCOM- 19890420
LR  - 20190903
IS  - 0036-5599 (Print)
IS  - 0036-5599 (Linking)
VI  - 23
IP  - 1
DP  - 1989
TI  - Prospective management of neonates with pelviureteric junction stenosis. 
      Therapeutic strategy based on 99m Tc-DPTA studies.
PG  - 31-6
AB  - A prospective therapeutic strategy based on separate glomerular filtration rate 
      (SGFR) was evaluated in 14 prenatally detected asymptomatic neonates, suspected 
      of having pelviureteric junction obstruction. The patients with low SGFR were 
      referred for pyeloplasty with the hope to improve the renal function. A marked 
      improvement occurred in only one patient, although the drainage function 
      (furosemide test) did improve in all cases. A conservative attitude was adopted 
      for those children with normal SGFR. In 6 of them, a progressive increase of SGFR 
      was noted, related to the normal maturation of the function, followed by a 
      stabilization in the normal range. In 1 patient, a sudden decrease of SGFR was 
      observed around 1 year and the patient was shifted into the surgical group. In 
      this patient, an initial partial response of the kidney to a furosemide injection 
      changed into a persistent non-response, whereas in the other non-operated 
      patients, partial or good response was always recorded, although the responses 
      were essentially variable on successive tests. On the basis of these data, the 
      protocol was slightly modified, the patients with persistent non-response to 
      furosemide after 6 months of life being shifted to the surgical group.
FAU - Piepsz, A
AU  - Piepsz A
AD  - Department of Radioisotopes, Free Universities of Brussels, Belgium.
FAU - Hall, M
AU  - Hall M
FAU - Ham, H R
AU  - Ham HR
FAU - Verboven, M
AU  - Verboven M
FAU - Collier, F
AU  - Collier F
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Scand J Urol Nephrol
JT  - Scandinavian journal of urology and nephrology
JID - 0114501
RN  - 0 (Organometallic Compounds)
RN  - 7440-26-8 (Technetium)
RN  - 7A314HQM0I (Pentetic Acid)
RN  - 7LXU5N7ZO5 (Furosemide)
RN  - VW78417PU1 (Technetium Tc 99m Pentetate)
SB  - IM
MH  - Clinical Protocols
MH  - Follow-Up Studies
MH  - Furosemide
MH  - Glomerular Filtration Rate
MH  - Humans
MH  - Infant, Newborn
MH  - Kidney/*diagnostic imaging
MH  - Kidney Pelvis/surgery
MH  - *Organometallic Compounds
MH  - *Pentetic Acid
MH  - Prenatal Diagnosis
MH  - Prospective Studies
MH  - Radioisotope Renography
MH  - *Technetium
MH  - Technetium Tc 99m Pentetate
MH  - Ureteral Obstruction/diagnostic imaging/*therapy
EDAT- 1989/01/01 00:00
MHDA- 1989/01/01 00:01
CRDT- 1989/01/01 00:00
PHST- 1989/01/01 00:00 [pubmed]
PHST- 1989/01/01 00:01 [medline]
PHST- 1989/01/01 00:00 [entrez]
AID - 10.1080/00365599.1989.11690428 [doi]
PST - ppublish
SO  - Scand J Urol Nephrol. 1989;23(1):31-6. doi: 10.1080/00365599.1989.11690428.