PMID- 26475647
OWN - NLM
STAT- MEDLINE
DCOM- 20161114
LR  - 20190402
IS  - 1444-2892 (Electronic)
IS  - 1443-9506 (Linking)
VI  - 25
IP  - 3
DP  - 2016 Mar
TI  - Circadian Rhythm of Infarct Size and Left Ventricular Function Evaluated with 
      Tissue Doppler Echocardiography in ST Elevation Myocardial Infarction.
PG  - 250-6
LID - S1443-9506(15)01382-7 [pii]
LID - 10.1016/j.hlc.2015.06.833 [doi]
AB  - BACKGROUND: We aimed to investigate the circadian rhythm on left ventricular (LV) 
      function and infarct size, according to the onset of ST elevation myocardial 
      infarction (STEMI), with echocardiography in patients with first STEMI 
      successfully revascularised with primary percutaneous coronary intervention 
      (PCI). METHODS: We conducted a retrospective analysis of 252 STEMI patients. 
      Patients were divided into the four, six-hour periods of the day. Conventional 
      and tissue Doppler imaging (TDI) echocardiography were performed within 48hours 
      after onset of chest pain. The average of peak systolic myocardial velocities 
      (Sm) in each of the four myocardial segments and LV ejection fraction (LVEF) were 
      calculated. RESULTS: A negative linear correlation was shown between CK-MB levels 
      and Sm (r= -0.209, p=0.001). There was an oscillation between time of day and 
      average of Sm. The lowest Sm and largest infarct size were in the period of 
      06:00-noon compared with period of noon-18:00 and 18:00-midnight (p=0.029 and 
      p=0.031, respectively). A secondary analysis showed that both LVEF and Sm were 
      lower in the midnight-noon group compared with the noon-midnight group (44.9+/-7.3% 
      versus 47.3+/-7.9%, p=0.018, and 7.6+/-1.4cm/s versus 8.2+/-1.6cm/s, p=0.003, 
      respectively). CONCLUSIONS: This study has shown that there was a circadian 
      rhythm of infarct size and LV function evaluated by echocardiography according to 
      time of STEMI onset. The largest infarct size and poor LV function occurred in 
      the midnight-noon period, in particular in the 06:00-noon period.
CI  - Copyright (c) 2015 Australian and New Zealand Society of Cardiac and Thoracic 
      Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). 
      Published by Elsevier B.V. All rights reserved.
FAU - Ari, Hatem
AU  - Ari H
AD  - Suleyman Demirel University, Faculty of Medicine, Cardiology Department, 
      Isparta/Turkey.
FAU - Sonmez, Osman
AU  - Sonmez O
AD  - Bezmialem Vakif University, Faculty of Medicine, Cardiology Department, 
      Istanbul/Turkey.
FAU - Koc, Fatih
AU  - Koc F
AD  - Selcuk University, Faculty of Medicine, Cardiology Department, Konya/Turkey.
FAU - Alihanoglu, Yusuf
AU  - Alihanoglu Y
AD  - Selcuk University, Faculty of Medicine, Cardiology Department, Konya/Turkey.
FAU - Ozdemir, Kurtulus
AU  - Ozdemir K
AD  - Selcuk University, Faculty of Medicine, Cardiology Department, Konya/Turkey.
FAU - Vatankulu, Mehmet Akif
AU  - Vatankulu MA
AD  - Bezmialem Vakif University, Faculty of Medicine, Cardiology Department, 
      Istanbul/Turkey. Electronic address: vatankulu@hotmail.com.
LA  - eng
PT  - Journal Article
DEP - 20150928
PL  - Australia
TA  - Heart Lung Circ
JT  - Heart, lung & circulation
JID - 100963739
SB  - IM
EIN - Heart Lung Circ. 2016 Nov;25(11):e158. Demir K [removed]. PMID: 27725094
MH  - Adult
MH  - Aged
MH  - *Circadian Rhythm
MH  - *Echocardiography, Doppler
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnostic imaging/*physiopathology
MH  - Percutaneous Coronary Intervention
MH  - Retrospective Studies
MH  - *Stroke Volume
MH  - *Ventricular Function, Left
OTO - NOTNLM
OT  - Circadian
OT  - Echocardiography
OT  - Left ventricular function
OT  - Myocardial infarct size
OT  - Myocardial infarction
OT  - Tissue Doppler
EDAT- 2015/10/18 06:00
MHDA- 2016/11/15 06:00
CRDT- 2015/10/18 06:00
PHST- 2015/05/03 00:00 [received]
PHST- 2015/06/29 00:00 [accepted]
PHST- 2015/10/18 06:00 [entrez]
PHST- 2015/10/18 06:00 [pubmed]
PHST- 2016/11/15 06:00 [medline]
AID - S1443-9506(15)01382-7 [pii]
AID - 10.1016/j.hlc.2015.06.833 [doi]
PST - ppublish
SO  - Heart Lung Circ. 2016 Mar;25(3):250-6. doi: 10.1016/j.hlc.2015.06.833. Epub 2015 
      Sep 28.