PMID- 26478259
OWN - NLM
STAT- MEDLINE
DCOM- 20170601
LR  - 20220317
IS  - 1445-2197 (Electronic)
IS  - 1445-1433 (Linking)
VI  - 87
IP  - 4
DP  - 2017 Apr
TI  - Long-term outcomes following laparoscopic anterior and Nissen fundoplication.
PG  - 300-304
LID - 10.1111/ans.13358 [doi]
AB  - BACKGROUND: Limited evidence exists to which operation gives best long-term 
      outcomes for gastro-oesophageal reflux disease. This study aimed to assess 
      long-term symptomatic outcome and satisfaction following laparoscopic anterior 
      (LA) or Nissen fundoplication in a specialist upper gastrointestinal unit. 
      METHODS: Patients who underwent primary LA or Nissen (LN) fundoplication between 
      May 1994 and June 2010 were identified from a prospectively collected database. 
      DeMeester, modified DeMeester, 'Gastrointestinal Symptom Rating Scale' scores and 
      patient satisfaction were assessed by questionnaire. RESULTS: A total of 387 
      patients underwent surgery and 246 patients (65%) completed questionnaires, with 
      181 LA patients and 65 LN patients. Median follow-up was 83 months for LA and 179 
      months for LN (P < 0.001). A total of 218/245 (89%) reported major improvement in 
      symptoms and 27 (11%) reported poor outcomes. There was no differences between LA 
      and LN for symptom scores at short (<5 years) or long-term follow-up (>5 years). 
      Women reported significantly higher DeMeester scores and lower satisfaction (P = 
      0.012). One hundred and eighteen (48%) patients were taking proton pump 
      inhibitors (PPI) at follow-up despite high satisfaction rates. CONCLUSION: LA and 
      LN have similar long-term results with patients reporting high satisfaction 
      levels. Women reported more symptoms and less satisfaction than men. Despite high 
      satisfaction rates a high percentage of patients take PPIs.
CI  - (c) 2015 Royal Australasian College of Surgeons.
FAU - Robertson, Andrew G N
AU  - Robertson AG
AD  - Department of Upper GI Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
FAU - Patel, Ravi N
AU  - Patel RN
AD  - Department of Upper GI Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
FAU - Couper, Graeme W
AU  - Couper GW
AD  - Department of Upper GI Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
FAU - de Beaux, Andrew C
AU  - de Beaux AC
AD  - Department of Upper GI Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
FAU - Paterson-Brown, Simon
AU  - Paterson-Brown S
AD  - Department of Upper GI Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
FAU - Lamb, Peter J
AU  - Lamb PJ
AD  - Department of Upper GI Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20151019
PL  - Australia
TA  - ANZ J Surg
JT  - ANZ journal of surgery
JID - 101086634
SB  - IM
MH  - Adult
MH  - Female
MH  - Fundoplication/*statistics & numerical data
MH  - Gastroesophageal Reflux/*surgery
MH  - Humans
MH  - Laparoscopy/*statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Patient Satisfaction/*statistics & numerical data
MH  - Prospective Studies
MH  - Quality of Life
MH  - Sex Factors
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
OTO - NOTNLM
OT  - fundoplication
OT  - general surgery
OT  - quality of life
OT  - upper gut
EDAT- 2015/10/20 06:00
MHDA- 2017/06/02 06:00
CRDT- 2015/10/20 06:00
PHST- 2015/09/09 00:00 [accepted]
PHST- 2015/10/20 06:00 [pubmed]
PHST- 2017/06/02 06:00 [medline]
PHST- 2015/10/20 06:00 [entrez]
AID - 10.1111/ans.13358 [doi]
PST - ppublish
SO  - ANZ J Surg. 2017 Apr;87(4):300-304. doi: 10.1111/ans.13358. Epub 2015 Oct 19.