PMID- 26482627 OWN - NLM STAT- MEDLINE DCOM- 20160915 LR - 20151113 IS - 1768-3181 (Electronic) IS - 0003-3928 (Linking) VI - 64 IP - 5 DP - 2015 Nov TI - [ST elevation myocardial infarction (STEMI) in patients aged 85 and over. Invasive management versus exclusive medical treatment: Departmental study]. PG - 345-51 LID - S0003-3928(15)00162-6 [pii] LID - 10.1016/j.ancard.2015.09.040 [doi] AB - INTRODUCTION: Percutaneous coronary intervention (PCI) and/or fibrinolysis for management of an ST elevation myocardial infarction (STEMI) are at high risk in the elderly. Is there any place for an invasive management in this particular population? METHODS: It is a single-center retrospective study (CHD Vendee, La Roche-sur-Yon) including patients aged 85 and over who had STEMI between January 2008 and December 2013, divided into two groups: coronary angiogram/fibrinolysis ("invasive") versus exclusive medical treatment ("non-invasive"), comparing mortality, morbidity, complications and loss of independence. RESULTS: Among the 1373 patients hospitalized for STEMI, 118 (8.6%) were included: 71 (60.2%) underwent an invasive procedure for reperfusion whereas 47 had "non-invasive" management. All cause mortality rate was higher in the "non-invasive" group (28% versus 45%; P=0.077 NS). The identified pejorative criteria are age, female gender, past history of severe valvular disease, and delay for primary care. No difference was found in intrahospital complication rate (23 vs 21; P=0.21) nor in loss of independence. CONCLUSION: The invasive management of STEMI in the elderly may reduce the one-year mortality rate without increasing morbidity. CI - Copyright (c) 2015 Elsevier Masson SAS. All rights reserved. FAU - Doizon, T AU - Doizon T AD - Service de cardiologie, CHD de Vendee, Les Oudairies, 85000 La Roche-sur-Yon, France. Electronic address: thomas.doizon@chd-vendee.fr. FAU - Orion, L AU - Orion L AD - Service de cardiologie, CHD de Vendee, Les Oudairies, 85000 La Roche-sur-Yon, France. FAU - Dimet, J AU - Dimet J AD - Service de recherche clinique, CHD de Vendee, Les Oudairies, 85000 La Roche-sur-Yon, France. FAU - Boiffard, E AU - Boiffard E AD - Service de cardiologie, CHD de Vendee, Les Oudairies, 85000 La Roche-sur-Yon, France. LA - fre PT - Comparative Study PT - English Abstract PT - Journal Article TT - Syndrome coronarien aigu avec sus-decalage du segment ST chez les patients de 85ans et plus. Prise en charge invasive versus traitement medical exclusif: etude departementale. DEP - 20151021 PL - France TA - Ann Cardiol Angeiol (Paris) JT - Annales de cardiologie et d'angeiologie JID - 0142167 SB - IM MH - Aged, 80 and over MH - Cardiovascular Diseases MH - Electrocardiography MH - Female MH - Humans MH - Male MH - Myocardial Infarction/physiopathology/*therapy MH - *Percutaneous Coronary Intervention MH - Retrospective Studies MH - *Thrombolytic Therapy OTO - NOTNLM OT - Elderly patients OT - Myocardial revascularization OT - Reperfusion myocardique OT - ST elevation myocardial infarction OT - Sujets ages OT - Syndrome coronarien aigu ST+ OT - Vendee EDAT- 2015/10/21 06:00 MHDA- 2016/09/16 06:00 CRDT- 2015/10/21 06:00 PHST- 2015/07/31 00:00 [received] PHST- 2015/09/03 00:00 [accepted] PHST- 2015/10/21 06:00 [entrez] PHST- 2015/10/21 06:00 [pubmed] PHST- 2016/09/16 06:00 [medline] AID - S0003-3928(15)00162-6 [pii] AID - 10.1016/j.ancard.2015.09.040 [doi] PST - ppublish SO - Ann Cardiol Angeiol (Paris). 2015 Nov;64(5):345-51. doi: 10.1016/j.ancard.2015.09.040. Epub 2015 Oct 21.