PMID- 26484908
OWN - NLM
STAT- MEDLINE
DCOM- 20161101
LR  - 20181113
IS  - 1875-8908 (Electronic)
IS  - 1387-2877 (Print)
IS  - 1387-2877 (Linking)
VI  - 49
IP  - 3
DP  - 2016
TI  - Higher Fasting Plasma Glucose Levels, within the Normal Range, are Associated 
      with Decreased Processing Speed in High Functioning Young Elderly.
PG  - 589-92
LID - 10.3233/JAD-150433 [doi]
AB  - We explored the association of plasma glucose levels within the normal range with 
      processing speed in high functioning young elderly, free of type 2 diabetes 
      mellitus (T2DM). A sample of 41 participants (mean age = 64.7, SD = 10; glucose 
      94.5 mg/dL, SD = 9.3), were examined with a computerized cognitive battery. 
      Hierarchical linear regression analysis showed that higher plasma glucose levels, 
      albeit within the normal range (<110 mg/dL), were associated with longer reaction 
      times (p <  0.01). These findings suggest that even in the subclinical range and 
      in the absence of T2DM, monitoring plasma glucose levels may have an impact on 
      cognitive function.
FAU - Raizes, Meytal
AU  - Raizes M
AD  - Behavioral Sciences, Academic College of Tel Aviv-Yaffo, Israel.
FAU - Elkana, Odelia
AU  - Elkana O
AD  - Behavioral Sciences, Academic College of Tel Aviv-Yaffo, Israel.
FAU - Franko, Motty
AU  - Franko M
AD  - Behavioral Sciences, Academic College of Tel Aviv-Yaffo, Israel.
FAU - Ravona Springer, Ramit
AU  - Ravona Springer R
AD  - Department of Psychiatry, Sheba Medical Center, Israel.
AD  - Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Segev, Shlomo
AU  - Segev S
AD  - Institute of Medical Screening, Sheba Medical Center Tel Hashomer, Israel.
FAU - Beeri, Michal Schnaider
AU  - Beeri MS
AD  - Joseph Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel.
AD  - The Icahn School of Medicine at Mount Sinai, Department of Psychiatry, New York, 
      NY, USA.
LA  - eng
GR  - R01 AG034087/AG/NIA NIH HHS/United States
PT  - Journal Article
PL  - Netherlands
TA  - J Alzheimers Dis
JT  - Journal of Alzheimer's disease : JAD
JID - 9814863
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Aged
MH  - Blood Glucose/*metabolism
MH  - Cognition/physiology
MH  - Diabetes Mellitus, Type 2/*blood/*physiopathology
MH  - Fasting/*physiology
MH  - Female
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Neuropsychological Tests
MH  - Psychomotor Performance/*physiology
MH  - Reaction Time/*physiology
MH  - Reference Values
PMC - PMC5753410
MID - NIHMS931084
OTO - NOTNLM
OT  - Plasma glucose level
OT  - cognitive function
OT  - processing speed
OT  - type 2 diabetes
EDAT- 2015/10/21 06:00
MHDA- 2016/11/02 06:00
PMCR- 2018/01/04
CRDT- 2015/10/21 06:00
PHST- 2015/10/21 06:00 [entrez]
PHST- 2015/10/21 06:00 [pubmed]
PHST- 2016/11/02 06:00 [medline]
PHST- 2018/01/04 00:00 [pmc-release]
AID - JAD150433 [pii]
AID - 10.3233/JAD-150433 [doi]
PST - ppublish
SO  - J Alzheimers Dis. 2016;49(3):589-92. doi: 10.3233/JAD-150433.