PMID- 26489973
OWN - NLM
STAT- MEDLINE
DCOM- 20160329
LR  - 20191210
IS  - 1540-8183 (Electronic)
IS  - 0896-4327 (Linking)
VI  - 28
IP  - 5
DP  - 2015 Oct
TI  - Safety and Efficacy of Immediate Rotational Atherectomy in Nondilatable Calcified 
      Coronary Lesions Complicated by Coronary Artery Dissection (RAISE).
PG  - 456-63
LID - 10.1111/joic.12232 [doi]
AB  - OBJECTIVES: To examine the safety and efficacy of immediate rotational 
      atherectomy (RA) in nondilatable calcified coronary lesions complicated by 
      coronary dissection during percutaneous coronary intervention (PCI). BACKGROUND: 
      In the presence of coronary dissection in nondilatable calcified coronary 
      lesions, conservative management is suggested to permit the dissection to heal 
      prior to treatment with RA. However, many patients have frequent angina attacks 
      and some patients develop serious complications during this period. METHODS: One 
      hundred and nighty-eight patients with severe coronary calcification underwent 
      PCI, and were randomized into immediate (n = 105) or delayed RA group (n = 93) 
      when coronary dissections occur. The primary endpoint of the present study was 
      all-cause death including cardiac and non-cardiac death in 4 years follow-up. 
      Non-fatal myocardial infarction, stent thrombosis, cardiac tamponade, stroke, 
      target lesion revascularization, New York Heart Association (NYHA) class IV heart 
      failure were analyzed as secondary end points. RESULTS: At a follow-up of 4 
      years, event-free survival rates were not statistically different between the 
      immediate and delayed RA group (81.9% vs 80.6%, P = 0.820). Rates of PCI- and 
      RA-related major adverse cardiac events (MACE) and severe RA-related 
      complications were not statistically different between groups. Luminal loss was 
      not significantly different between the immediate and delayed RA group as 
      evaluated by Intravascular ultrasound (IVUS). Two cases in the delayed RA group 
      experienced myocardial infarction during the 4-week waiting. CONCLUSION: This 
      study indicates that immediate RA during PCI is safe and effective in patients 
      with coronary artery dissection.
CI  - (c) 2015, Wiley Periodicals, Inc.
FAU - Zhang, Dongwei
AU  - Zhang D
AD  - Department of Cardiology, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
FAU - Hu, Jianqiang
AU  - Hu J
AD  - Department of Cardiology, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
FAU - Man, Wanrong
AU  - Man W
AD  - Department of Cardiology, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
FAU - Wang, Tingting
AU  - Wang T
AD  - Department of Cardiology, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
FAU - Zhang, Mingming
AU  - Zhang M
AD  - Department of Cardiology, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
FAU - Lin, Jie
AU  - Lin J
AD  - Department of Cardiology, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
FAU - Narsinh, Kazim
AU  - Narsinh K
AD  - Department of Radiology, University of California San Diego, La Jolla, CA.
FAU - Zhang, Lei
AU  - Zhang L
AD  - Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
FAU - Li, Chengxiang
AU  - Li C
AD  - Department of Cardiology, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
FAU - Sun, Dongdong
AU  - Sun D
AD  - Department of Cardiology, Xijing Hospital, Fourth Military Medical University, 
      Xi'an, Shaanxi, China.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Interv Cardiol
JT  - Journal of interventional cardiology
JID - 8907826
SB  - IM
MH  - Aged
MH  - *Atherectomy, Coronary/adverse effects/methods
MH  - China
MH  - Coronary Angiography/methods
MH  - *Coronary Artery Disease/diagnosis/mortality/surgery
MH  - Early Medical Intervention
MH  - Female
MH  - Humans
MH  - *Intraoperative Complications/diagnosis/surgery
MH  - Male
MH  - Middle Aged
MH  - Outcome Assessment, Health Care
MH  - Percutaneous Coronary Intervention/*adverse effects
MH  - Survival Analysis
MH  - Time Factors
MH  - Treatment Outcome
MH  - *Vascular Calcification/diagnosis/mortality/surgery
EDAT- 2015/10/23 06:00
MHDA- 2016/03/30 06:00
CRDT- 2015/10/23 06:00
PHST- 2015/10/23 06:00 [entrez]
PHST- 2015/10/23 06:00 [pubmed]
PHST- 2016/03/30 06:00 [medline]
AID - 10.1111/joic.12232 [doi]
PST - ppublish
SO  - J Interv Cardiol. 2015 Oct;28(5):456-63. doi: 10.1111/joic.12232.