PMID- 26490932
OWN - NLM
STAT- MEDLINE
DCOM- 20161011
LR  - 20181202
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 23
IP  - 4
DP  - 2016 Feb
TI  - Serum concentrations of PCBs and OCPs among prepubertal Korean children.
PG  - 3536-47
LID - 10.1007/s11356-015-5578-0 [doi]
AB  - Although children are more vulnerable than adults to environmental hazards, due 
      to their physiological and behavioral characteristics, few studies have assessed 
      their internal exposure to persistent organic pollutants (POPs). The objective of 
      this study was to determine the serum levels of certain polychlorinated biphenyls 
      (PCBs) and organochlorine pesticides (OCPs) among pre-pubertal children in Korea 
      and examine their variation with age and gender. We analyzed a total of 51 POPs 
      in 214 children (age range, 7-9 years), using data from the Ewha Birth and Growth 
      Cohort Study. To examine change over time, POP concentrations were measured at 
      both 7 and 9 years of age in a sub-cohort of 26 children. The median and 
      interquartile range (IQR, 25th to 75th percentiles) data for the sum of PCB 
      congeners was 26.44 ng/g lipid (18.27-37.63 ng/g lipid). The median (IQR) 
      concentration for the sum of OCPs was 74.82 ng/g lipid (51.11-112.45 ng/g lipid). 
      Our results showed significant increases in serum concentrations of total PCBs 
      with age (p = 0.0001), no gender dependence of total PCBs (p = 0.38) and total 
      OCPs (p = 0.12), and strong correlations between individual POPs. Childhood 
      exposure to POPs was relatively low compared to other studies carried out in 
      different countries. However, even though the use of POPs has been banned since 
      2001, our results indicated that children in the general population are still 
      exposed to various POPs. Because long-term, low-level exposure to POPs in the 
      general population remains a concern for human health, future research should 
      examine major routes of exposure and identification of risk factors.
FAU - Park, Su Hyun
AU  - Park SH
AD  - Department of Preventive Medicine, School of Medicine, Ewha Womans University, 
      1071, Anyangcheon-ro, Yangcheon-ku, Seoul, 158-710, Republic of Korea. 
      shp323@ewha.ac.kr.
FAU - Hong, Young Sun
AU  - Hong YS
AD  - Department of Internal Medicine, School of Medicine, Ewha Womans University, 
      Seoul, Korea. imhys@ewha.ac.kr.
FAU - Ha, Eun-Hee
AU  - Ha EH
AD  - Department of Preventive Medicine, School of Medicine, Ewha Womans University, 
      1071, Anyangcheon-ro, Yangcheon-ku, Seoul, 158-710, Republic of Korea. 
      eunheeha@ewha.ac.kr.
FAU - Park, Hyesook
AU  - Park H
AD  - Department of Preventive Medicine, School of Medicine, Ewha Womans University, 
      1071, Anyangcheon-ro, Yangcheon-ku, Seoul, 158-710, Republic of Korea. 
      hpark@ewha.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20151021
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hazardous Substances)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
EIN - Environ Sci Pollut Res Int. 2016 Apr;23(7):7070. PMID: 26884236
MH  - Adolescent
MH  - Adult
MH  - Aging/*blood
MH  - Child, Preschool
MH  - Cohort Studies
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Hazardous Substances/*blood
MH  - Humans
MH  - Hydrocarbons, Chlorinated/blood
MH  - Male
MH  - Pesticides/*blood
MH  - Polychlorinated Biphenyls/*blood
MH  - Republic of Korea
OTO - NOTNLM
OT  - Biomonitoring
OT  - Children
OT  - Exposure assessment
OT  - Persistent organic pollutants
EDAT- 2015/10/23 06:00
MHDA- 2016/10/12 06:00
CRDT- 2015/10/23 06:00
PHST- 2015/07/19 00:00 [received]
PHST- 2015/10/07 00:00 [accepted]
PHST- 2015/10/23 06:00 [entrez]
PHST- 2015/10/23 06:00 [pubmed]
PHST- 2016/10/12 06:00 [medline]
AID - 10.1007/s11356-015-5578-0 [pii]
AID - 10.1007/s11356-015-5578-0 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2016 Feb;23(4):3536-47. doi: 
      10.1007/s11356-015-5578-0. Epub 2015 Oct 21.