PMID- 26492711
OWN - NLM
STAT- MEDLINE
DCOM- 20151106
LR  - 20191113
IS  - 0017-0011 (Print)
IS  - 0017-0011 (Linking)
VI  - 86
IP  - 8
DP  - 2015 Aug
TI  - [Analysis of screening tests for Streptococcus agalactiae in pregnant women from 
      the West Pomeranian region].
PG  - 616-21
AB  - OBJECTIVE: The aim of the study was to determine the degree of colonization 
      Streptococcus agalactiae (GBS--Group B Streptococcus) in women at 35.-37. weeks 
      of pregnancy and to evaluate drug susceptibility of the isolated strains. 
      MATERIAL AND METHODS: We analyzed the results of 1111 tests for GBS colonization 
      performed between 2010-2013 in pregnant women (aged 16-40) from the West 
      Pomeranian region. Swabs were taken from the vagina and the anus of the study 
      subjects at 35.-37. weeks of pregnancy Materials were cultured on Granada Agar 
      and in selective Todd-Hewitt broth, which was next cultured on Granada Agar The 
      degree of GBS colonization was determined by the semi-quantitative method on 
      solid media. The strains were tested for susceptibility to penicillin, 
      erythromycin and clindamycin by disc diffusion method according to the EUCAST 
      standards. RESULTS: Positive cultures for S. agalactiae were found in 22.5% of 
      the pregnant women. The highest (25.4%) and the lowest (15.9%) rates of GBS 
      colonization were observed in the age groups of 31-35 and 16-20 years, 
      respectively Massive GBS colonization was detected in 68.4% of pregnant subjects, 
      with the highest and the lowest rates in the age groups of 31-35 and 16-20 years, 
      (75.3% and 50.0%, respectively). All isolated GBS strains were sensitive to 
      penicillin. Macrolide, lincosamide and streptogramin B resistance (MLSB) was 
      found in 28% of the isolates, resistance only to erythromycin (phenotype M) in 2% 
      of the strains. There were no significant differences in the degree of GBS 
      colonization and drug sensitivity of GBS strains versus the year of our 
      examination. CONCLUSIONS: Monitoring for GBS colonization in the last weeks of 
      pregnancy seems to be necessary for effective prevention of S. agalactiae 
      infections.
FAU - Pruss, Agata
AU  - Pruss A
FAU - Galant, Katarzyna
AU  - Galant K
FAU - Giedrys-Kalemba, Stefania
AU  - Giedrys-Kalemba S
LA  - pol
PT  - English Abstract
PT  - Journal Article
TT  - Analiza badan przesiewowych w kierunku Streptococcus agalactiae u kobiet w ciazy 
      z regionu Pomorza Zachodniego.
PL  - Poland
TA  - Ginekol Pol
JT  - Ginekologia polska
JID - 0374641
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Anal Canal/microbiology
MH  - Bacterial Load
MH  - Drug Resistance, Bacterial
MH  - Female
MH  - Humans
MH  - Microbial Sensitivity Tests/methods
MH  - Poland
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*microbiology
MH  - *Pregnancy Trimester, Third
MH  - Specimen Handling/methods
MH  - Streptococcal Infections/*microbiology
MH  - Streptococcus agalactiae/*isolation & purification
MH  - Vagina/microbiology
MH  - Young Adult
EDAT- 2015/10/24 06:00
MHDA- 2015/11/07 06:00
CRDT- 2015/10/24 06:00
PHST- 2015/10/24 06:00 [entrez]
PHST- 2015/10/24 06:00 [pubmed]
PHST- 2015/11/07 06:00 [medline]
AID - 10.17772/gp/57858 [doi]
PST - ppublish
SO  - Ginekol Pol. 2015 Aug;86(8):616-21. doi: 10.17772/gp/57858.