PMID- 26499875
OWN - NLM
STAT- MEDLINE
DCOM- 20160408
LR  - 20181113
IS  - 1471-2415 (Electronic)
IS  - 1471-2415 (Linking)
VI  - 15
DP  - 2015 Oct 24
TI  - Central corneal sensitivity after small incision lenticule extraction versus 
      femtosecond laser-assisted LASIK for myopia: a meta-analysis of comparative 
      studies.
PG  - 141
LID - 10.1186/s12886-015-0129-5 [doi]
LID - 141
AB  - BACKGROUND: The aim of this study was to evaluate central corneal sensitivity 
      after small incision lenticule extraction (SMILE) versus femtosecond 
      laser-assisted laser in situ keratomileusis (FS-LASIK) for myopia. METHODS: 
      Eligible studies were identified by systematically searching PubMed, the Cochrane 
      Library, Embase and the Chinese Biomedicine Database. Central corneal sensitivity 
      after SMILE versus FS-LASIK was assessed by the pooled weighted mean differences 
      (WMDs) of the reduction from pre-operation levels to 1 week, 1, 3 and 6 months 
      following the operation. The quality of the included literature was assessed by 
      the Quality Index. Data were synthesized by Stata 12.0 SE for Windows. RESULTS: 
      Five studies involving 245 patients (363 eyes; 189 eyes in the FS-LASIK group and 
      174 eyes in the SMILE group) were included in the meta-analysis. The pooled 
      results showed that there were no significant differences in central corneal 
      sensitivity between FS-LASIK and SMILE before surgery (WMD = 0 mm, 95 % CI: -0.23 
      to -0.23, p = 0.998). At 1 week, 1 and 3 months after surgery, the central 
      corneal sensitivity after FS-LASIK was lower than with SMILE (WMD = -17.35 mm, 95 
      % CI: -26.54 to -8.16, p <0.001; WMD = -17.52 mm, 95 % CI: -25.10 to -9.94, p 
      <0.001; WMD = -14.64 mm, 95 % CI: -20.08 to -9.21, p <0.001, respectively). 
      However, central corneal sensitivity after FS-LASIK was similar with SMILE 6 
      months after surgery (WMD = -2.02 mm, 95 % CI: -4.23 to 0.19, p = 0.074). 
      CONCLUSION: Central corneal sensitivity exhibited a small decrease and a faster 
      recovery after the SMILE procedure compared to FS-LASIK during the first three 
      postoperative months. Corneal sensitivity after SMILE and FS-LASIK was similar at 
      6 months after surgery. However, these results should be interpreted with caution 
      due to the limited number of studies.
FAU - He, Miao
AU  - He M
AD  - Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen 
      University, 54SXianlie Road, Guangzhou, 510060, China. 943602453@qq.com.
FAU - Huang, Wenyong
AU  - Huang W
AD  - Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen 
      University, 54SXianlie Road, Guangzhou, 510060, China. andyhwyz@aliyun.com.
FAU - Zhong, Xingwu
AU  - Zhong X
AD  - Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen 
      University, 54SXianlie Road, Guangzhou, 510060, China. zhongxwu@mail.sysu.edu.cn.
AD  - Hainan Eye Hospital, Zhongshan Ophthalmic Center, Sun Yat-sen University, Haikou, 
      570311, China. zhongxwu@mail.sysu.edu.cn.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20151024
PL  - England
TA  - BMC Ophthalmol
JT  - BMC ophthalmology
JID - 100967802
SB  - IM
MH  - Adult
MH  - Cornea/*physiology
MH  - Humans
MH  - Keratomileusis, Laser In Situ/*methods
MH  - Lasers, Excimer/*therapeutic use
MH  - Myopia/physiopathology/*surgery
MH  - Prospective Studies
MH  - Visual Acuity/physiology
PMC - PMC4619500
EDAT- 2015/10/27 06:00
MHDA- 2016/04/09 06:00
PMCR- 2015/10/24
CRDT- 2015/10/27 06:00
PHST- 2015/04/06 00:00 [received]
PHST- 2015/10/12 00:00 [accepted]
PHST- 2015/10/27 06:00 [entrez]
PHST- 2015/10/27 06:00 [pubmed]
PHST- 2016/04/09 06:00 [medline]
PHST- 2015/10/24 00:00 [pmc-release]
AID - 10.1186/s12886-015-0129-5 [pii]
AID - 129 [pii]
AID - 10.1186/s12886-015-0129-5 [doi]
PST - epublish
SO  - BMC Ophthalmol. 2015 Oct 24;15:141. doi: 10.1186/s12886-015-0129-5.