PMID- 26500517
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151027
LR  - 20220317
IS  - 1662-5161 (Print)
IS  - 1662-5161 (Electronic)
IS  - 1662-5161 (Linking)
VI  - 9
DP  - 2015
TI  - Distinct neural correlates for attention lapses in patients with schizophrenia 
      and healthy participants.
PG  - 502
LID - 10.3389/fnhum.2015.00502 [doi]
LID - 502
AB  - Momentary lapses in attention are common in healthy populations. This phenomenon 
      has recently received increased investigation, particularly in relationship to 
      the default mode network (DMN). Previous research has suggested that these lapses 
      may be due to intrusive task-irrelevant thoughts. The study of this phenomenon in 
      schizophrenia, which is characterized by a wide variety of cognitive deficits 
      including deficits in attention, has not previously been explored. We used the AX 
      Continuous Performance Task to investigate attention lapses in healthy 
      participants as well as patients with schizophrenia. We found distinct patterns 
      of network activation between these two groups. Lapses in healthy participants 
      were associated with DMN activation, while in patients, the same behavioral 
      phenomenon was associated with deactivations in frontal-parietal control network 
      (FPCN) regions. When considered in contrast to the results observed in healthy 
      participants, these results suggest an additional origin of attention lapses in 
      patients derived from a loss of task-related context, rather than intrusive 
      task-irrelevant thoughts.
FAU - Phillips, Ryan C
AU  - Phillips RC
AD  - Translational Cognitive and Affective Neuroscience Lab, UC Davis Center for 
      Neuroscience, University of California, Davis Davis, CA, USA.
FAU - Salo, Taylor
AU  - Salo T
AD  - Translational Cognitive and Affective Neuroscience Lab, UC Davis Center for 
      Neuroscience, University of California, Davis Davis, CA, USA.
FAU - Carter, Cameron S
AU  - Carter CS
AD  - Translational Cognitive and Affective Neuroscience Lab, UC Davis Center for 
      Neuroscience, University of California, Davis Davis, CA, USA.
LA  - eng
PT  - Journal Article
DEP - 20151006
PL  - Switzerland
TA  - Front Hum Neurosci
JT  - Frontiers in human neuroscience
JID - 101477954
PMC - PMC4594500
OTO - NOTNLM
OT  - attention lapses
OT  - default mode network
OT  - fMRI
OT  - mind wandering
OT  - schizophrenia
EDAT- 2015/10/27 06:00
MHDA- 2015/10/27 06:01
PMCR- 2015/01/01
CRDT- 2015/10/27 06:00
PHST- 2015/03/30 00:00 [received]
PHST- 2015/08/28 00:00 [accepted]
PHST- 2015/10/27 06:00 [entrez]
PHST- 2015/10/27 06:00 [pubmed]
PHST- 2015/10/27 06:01 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
AID - 10.3389/fnhum.2015.00502 [doi]
PST - epublish
SO  - Front Hum Neurosci. 2015 Oct 6;9:502. doi: 10.3389/fnhum.2015.00502. eCollection 
      2015.