PMID- 26504643
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151027
LR  - 20200930
IS  - 2156-7085 (Print)
IS  - 2156-7085 (Electronic)
IS  - 2156-7085 (Linking)
VI  - 6
IP  - 10
DP  - 2015 Oct 1
TI  - In vivo three-dimensional characterization of the adult zebrafish brain using a 
      1325 nm spectral-domain optical coherence tomography system with the 27 frame/s 
      video rate.
PG  - 3932-40
LID - 10.1364/BOE.6.003932 [doi]
AB  - In this study, a spectral-domain optical coherence tomography (SD-OCT) system was 
      used for noninvasive imaging of the adult zebrafish brain. Based on a 1325 nm 
      light source and two high-speed galvo mirrors, our SD-OCT system can offer a 
      large field of view of brain morphology with high resolution (12 mum axial and 13 
      mum lateral) at video rate (27 frame/s). In vivo imaging of both the control and 
      injured brain was performed using adult zebrafish model. The recovered results 
      revealed that olfactory bulb, optic commissure, telencephalon, tectum opticum, 
      cerebellum, medulla, preglomerular complex and posterior tuberculum could be 
      clearly identified in the cross-sectional SD-OCT images of the adult zebrafish 
      brain. The reconstructed results also suggested that SD-OCT can be used for 
      diagnosis and monitoring of traumatic brain injury. In particular, we found the 
      reconstructed volumetric SD-OCT images enable a comprehensive three-dimensional 
      characterization of the control or injured brain in the intact zebrafish.
FAU - Zhang, Jian
AU  - Zhang J
AD  - Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
FAU - Ge, Wei
AU  - Ge W
AD  - Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
FAU - Yuan, Zhen
AU  - Yuan Z
AD  - Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
LA  - eng
PT  - Journal Article
DEP - 20150911
PL  - United States
TA  - Biomed Opt Express
JT  - Biomedical optics express
JID - 101540630
PMC - PMC4605052
OTO - NOTNLM
OT  - (110.4500) Optical coherence tomography
OT  - (170.0110) Imaging systems
OT  - (170.3880) Medical and biological imaging
EDAT- 2015/10/28 06:00
MHDA- 2015/10/28 06:01
PMCR- 2015/09/11
CRDT- 2015/10/28 06:00
PHST- 2015/05/04 00:00 [received]
PHST- 2015/08/04 00:00 [revised]
PHST- 2015/09/08 00:00 [accepted]
PHST- 2015/10/28 06:00 [entrez]
PHST- 2015/10/28 06:00 [pubmed]
PHST- 2015/10/28 06:01 [medline]
PHST- 2015/09/11 00:00 [pmc-release]
AID - 240165 [pii]
AID - 10.1364/BOE.6.003932 [doi]
PST - epublish
SO  - Biomed Opt Express. 2015 Sep 11;6(10):3932-40. doi: 10.1364/BOE.6.003932. 
      eCollection 2015 Oct 1.