PMID- 26509999
OWN - NLM
STAT- MEDLINE
DCOM- 20170309
LR  - 20220419
IS  - 1937-1578 (Electronic)
IS  - 1935-1089 (Linking)
VI  - 10
IP  - 3
DP  - 2016 Summer
TI  - POLYPOIDAL CHOROIDAL VASCULOPATHY SECONDARY TO A STABLE CHOROIDAL NEVUS.
PG  - 221-4
LID - 10.1097/ICB.0000000000000233 [doi]
AB  - PURPOSE: Choroidal nevus is the most common ocular fundus tumor in adults. 
      Previous studies have widely discussed the features of choroidal 
      neovascularization secondary to nevus and its treatment options. Polypoidal 
      choroidal vasculopathy (PCV) is an exudative chorioretinopathy that is often 
      underdiagnosed. Clinical features, natural history, and treatment response of PCV 
      are distinct from occult choroidal neovascularization. Polypoidal choroidal 
      vasculopathy secondary to choroidal nevus has not been previously documented. We 
      report a patient with a history of stable choroidal nevus who developed a 
      polypoidal lesion at the edge of the nevus lesion. METHODS: A white woman who 
      presented with a choroidal nevus and clinical features of PCV was examined using 
      fundoscopy, optical coherence tomography, fluorescein angiography, and 
      indocyanine green angiography. RESULTS: A polypoidal lesion with an associated 
      branching vascular network adjacent to the nevus was demonstrated by optical 
      coherence tomography, fluorescein angiography, and indocyanine green angiography. 
      The patient was asymptomatic and was managed conservatively. CONCLUSION: Our case 
      showed that PCV developing in association with a stable choroidal nevus. 
      Pathogenic mechanisms of this condition may include chronic degenerative or 
      inflammatory changes at the level of the retinal pigment epithelium resulting in 
      vascular changes. Unlike treatment of occult choroidal neovascularization 
      secondary to nevus, optimal management of PCV secondary to nevus may vary. 
      Indocyanine green angiography is the gold standard for the diagnosis of PCV and 
      is a useful investigation in atypical choroidal neovascularization.
FAU - Wong, James G
AU  - Wong JG
AD  - *Strathfield Retina Clinic, Sydney, Australia; daggerMedical Retina Unit, Sydney Eye 
      Hospital, Sydney, Australia; double daggerSave Sight Institute, University of Sydney, Sydney, 
      Australia;  section signSchool of Medicine, Faculty of Medicine and Biomedical Sciences, 
      University of Queensland, Brisbane, Australia;  paragraph signDepartment of Ophthalmology, 
      Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, 
      Malaysia; and **Ophthalmology Clinic, Children's Hospital Westmead, Sydney, 
      Australia.
FAU - Lai, Xin Jie
AU  - Lai XJ
FAU - Sarafian, Richard Y
AU  - Sarafian RY
FAU - Wong, Hon Seng
AU  - Wong HS
FAU - Smith, Jeremy B
AU  - Smith JB
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Retin Cases Brief Rep
JT  - Retinal cases & brief reports
JID - 101298744
SB  - IM
MH  - Choroid Neoplasms/*complications/pathology
MH  - Choroidal Neovascularization/*etiology/pathology
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Nevus/*complications/pathology
MH  - Retinal Pigment Epithelium/pathology
EDAT- 2015/10/29 06:00
MHDA- 2017/03/10 06:00
CRDT- 2015/10/29 06:00
PHST- 2015/10/29 06:00 [entrez]
PHST- 2015/10/29 06:00 [pubmed]
PHST- 2017/03/10 06:00 [medline]
AID - 10.1097/ICB.0000000000000233 [doi]
PST - ppublish
SO  - Retin Cases Brief Rep. 2016 Summer;10(3):221-4. doi: 
      10.1097/ICB.0000000000000233.