PMID- 26510553
OWN - NLM
STAT- MEDLINE
DCOM- 20170418
LR  - 20181113
IS  - 1615-2573 (Electronic)
IS  - 0910-8327 (Linking)
VI  - 31
IP  - 8
DP  - 2016 Aug
TI  - Right coronary cusp as a new window of ablation for pilsicainide-induced 
      ventricular premature contractions in a patient with Brugada syndrome.
PG  - 1397-401
LID - 10.1007/s00380-015-0760-3 [doi]
AB  - A previous study demonstrated that ventricular premature contractions (VPCs) and 
      ventricular fibrillation (VF) are provoked during sodium channel blocker 
      challenge tests in Brugada syndrome (BrS) patients (Morita et al., J Am Coll 
      Cardiol 42:1624-1631, 2003). The right ventricular outflow tract (RVOT) is a 
      major arrhythmogenic focus and isolated VPCs originating from that area have been 
      shown to initiate VF (Kakishita et al., J Am Coll Cardiol 36:1646-1653, 2000). 
      Here, we describe a case report of a BrS patient with VPCs arising from the 
      posterior aspect of the RVOT epicardium which was provoked by a low-dose of 
      pilsicainide, a pure sodium channel blocker, and was successfully ablated from 
      the right coronary cusp.
FAU - Yamasaki, Hiro
AU  - Yamasaki H
AD  - Cardiovascular Division, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. hyamasaki@mail.goo.ne.jp.
FAU - Tada, Hiroshi
AU  - Tada H
AD  - Department of Cardiovascular Medicine, Faculty of Medical Sciences, University of 
      Fukui, Yoshida-gun, Fukui, Japan.
FAU - Sekiguchi, Yukio
AU  - Sekiguchi Y
AD  - Cardiovascular Division, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
FAU - Aonuma, Kazutaka
AU  - Aonuma K
AD  - Cardiovascular Division, Faculty of Medicine, University of Tsukuba, 1-1-1 
      Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20151028
PL  - Japan
TA  - Heart Vessels
JT  - Heart and vessels
JID - 8511258
RN  - 0 (Sodium Channel Blockers)
RN  - 98PI200987 (Lidocaine)
RN  - AV0X7V6CSE (pilsicainide)
SB  - IM
MH  - Adult
MH  - Brugada Syndrome/*drug therapy
MH  - Electrocardiography
MH  - Electrophysiologic Techniques, Cardiac
MH  - Heart Ventricles/*drug effects
MH  - Humans
MH  - Lidocaine/adverse effects/*analogs & derivatives
MH  - Male
MH  - Pericardium/physiopathology
MH  - Sodium Channel Blockers/*adverse effects
MH  - Ventricular Premature Complexes/chemically induced/*diagnosis/surgery
OTO - NOTNLM
OT  - Brugada syndrome
OT  - Ventricular premature contractions
EDAT- 2015/10/30 06:00
MHDA- 2017/04/19 06:00
CRDT- 2015/10/30 06:00
PHST- 2014/09/03 00:00 [received]
PHST- 2015/10/02 00:00 [accepted]
PHST- 2015/10/30 06:00 [entrez]
PHST- 2015/10/30 06:00 [pubmed]
PHST- 2017/04/19 06:00 [medline]
AID - 10.1007/s00380-015-0760-3 [pii]
AID - 10.1007/s00380-015-0760-3 [doi]
PST - ppublish
SO  - Heart Vessels. 2016 Aug;31(8):1397-401. doi: 10.1007/s00380-015-0760-3. Epub 2015 
      Oct 28.