PMID- 26511614
OWN - NLM
STAT- MEDLINE
DCOM- 20160510
LR  - 20230216
IS  - 1541-6100 (Electronic)
IS  - 0022-3166 (Linking)
VI  - 146
IP  - 1
DP  - 2016 Jan
TI  - Total and Full-Fat, but Not Low-Fat, Dairy Product Intakes are Inversely 
      Associated with Metabolic Syndrome in Adults.
PG  - 81-9
LID - 10.3945/jn.115.220699 [doi]
AB  - BACKGROUND: Growing evidence suggests that dairy products may have beneficial 
      cardiometabolic effects. The current guidelines, however, limit the intake of 
      full-fat dairy products. OBJECTIVE: We investigated the association of dairy 
      consumption, types of dairy products, and dairy fat content with metabolic 
      syndrome (MetSyn). METHODS: We analyzed baseline data of the Brazilian 
      Longitudinal Study of Adult Health (ELSA-Brasil), a multicenter cohort study of 
      15,105 adults aged 35-74 y. We excluded participants with known diabetes, 
      cardiovascular diseases, or other chronic diseases, and those who had extreme 
      values of energy intake, leaving 9835 for analysis. Dairy consumption was 
      assessed by a food-frequency questionnaire. We computed servings per day for 
      total and subgroups of dairy intake. We computed a metabolic risk score 
      (MetScore) as the mean z score of waist circumference, systolic blood pressure, 
      HDL cholesterol (negative z score), fasting triglycerides, and fasting glucose. 
      We performed multivariable linear regression to test the association of servings 
      per day of dairy products with MetScore. RESULTS: In analyses that adjusted for 
      demographics, menopausal status, family history of diabetes, dietary intake, 
      nondietary lifestyle factors, and body mass index, we observed a graded inverse 
      association for MetScore with total dairy (-0.044 +/- 0.01, P = 0.009 for each 
      additional dairy servings per day) and full-fat dairy (-0.126 +/- 0.03, P < 0.001) 
      but not with low-fat dairy intake. Associations were no longer present after 
      additional adjustments for dairy-derived saturated fatty acids. CONCLUSIONS: 
      Total and especially full-fat dairy food intakes are inversely and independently 
      associated with metabolic syndrome in middle-aged and older adults, associations 
      that seem to be mediated by dairy saturated fatty acids. Dietary recommendations 
      to avoid full-fat dairy intake are not supported by our findings.
CI  - (c) 2016 American Society for Nutrition.
FAU - Drehmer, Michele
AU  - Drehmer M
AD  - Department of Nutrition and Food and Nutrition Research Center, Postgraduate 
      Program in Epidemiology, School of Medicine, Federal University of Rio Grande, 
      Porto Alegre, Brazil; michele.drehmer@ufrgs.br.
FAU - Pereira, Mark A
AU  - Pereira MA
AD  - Division of Epidemiology and Community Health, School of Public Health, 
      University of Minnesota, Minneapolis, MN;
FAU - Schmidt, Maria Ines
AU  - Schmidt MI
AD  - Department of Social Medicine, and Postgraduate Program in Epidemiology, School 
      of Medicine, Federal University of Rio Grande, Porto Alegre, Brazil;
FAU - Alvim, Sheila
AU  - Alvim S
AD  - Institute of Collective Health, Federal University of Bahia, Salvador, Brazil; 
      and.
FAU - Lotufo, Paulo A
AU  - Lotufo PA
AD  - Center for Clinical and Epidemiologic Research, University of Sao Paulo, Sao 
      Paulo, Brazil.
FAU - Luft, Vivian C
AU  - Luft VC
AD  - Department of Nutrition and Food and Nutrition Research Center, Postgraduate 
      Program in Epidemiology, School of Medicine, Federal University of Rio Grande, 
      Porto Alegre, Brazil;
FAU - Duncan, Bruce B
AU  - Duncan BB
AD  - Department of Social Medicine, and Postgraduate Program in Epidemiology, School 
      of Medicine, Federal University of Rio Grande, Porto Alegre, Brazil;
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20151028
PL  - United States
TA  - J Nutr
JT  - The Journal of nutrition
JID - 0404243
RN  - 0 (Blood Glucose)
RN  - 0 (Cholesterol, HDL)
RN  - 0 (Dietary Fats)
RN  - 0 (Fatty Acids)
RN  - 0 (Triglycerides)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Glucose/metabolism
MH  - Blood Pressure
MH  - Body Mass Index
MH  - Brazil
MH  - Cholesterol, HDL/blood
MH  - Cross-Sectional Studies
MH  - Dairy Products/*analysis
MH  - Dietary Fats/administration & dosage/*analysis
MH  - Energy Intake
MH  - Fasting
MH  - Fatty Acids/administration & dosage
MH  - Female
MH  - Humans
MH  - Linear Models
MH  - Longitudinal Studies
MH  - Male
MH  - Metabolic Syndrome/*blood
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Socioeconomic Factors
MH  - Triglycerides/blood
MH  - Waist Circumference
OTO - NOTNLM
OT  - cohort study
OT  - dairy consumption
OT  - diabetes
OT  - metabolic syndrome
OT  - saturated fatty acids
EDAT- 2015/10/30 06:00
MHDA- 2016/05/11 06:00
CRDT- 2015/10/30 06:00
PHST- 2015/07/15 00:00 [received]
PHST- 2015/10/08 00:00 [accepted]
PHST- 2015/10/30 06:00 [entrez]
PHST- 2015/10/30 06:00 [pubmed]
PHST- 2016/05/11 06:00 [medline]
AID - S0022-3166(22)08973-8 [pii]
AID - 10.3945/jn.115.220699 [doi]
PST - ppublish
SO  - J Nutr. 2016 Jan;146(1):81-9. doi: 10.3945/jn.115.220699. Epub 2015 Oct 28.