PMID- 26512134
OWN - NLM
STAT- MEDLINE
DCOM- 20161101
LR  - 20161230
IS  - 1876-4479 (Electronic)
IS  - 1873-9946 (Linking)
VI  - 10
IP  - 2
DP  - 2016 Feb
TI  - Classifying Back Pain and Peripheral Joint Complaints in Inflammatory Bowel 
      Disease Patients: A Prospective Longitudinal Follow-up Study.
PG  - 166-75
LID - 10.1093/ecco-jcc/jjv195 [doi]
AB  - BACKGROUND AND AIMS: Peripheral joint complaints [pJTC] and chronic back pain 
      [CBP] are the most common extra-intestinal manifestations in patients with 
      inflammatory bowel disease [IBD]. This prospective study evaluates variables 
      associated with joint/back pain, including IBD disease activity. METHODS: IBD 
      patients with back pain >/= 3 months and/or peripheral joint pain/swelling [n = 
      155], and IBD patients without joint complaints [n = 100; controls], were 
      followed for a period of 1 year. Patients were classified as having 
      SpondyloArthritis [SpA] according to several sets of criteria. Statistical 
      analysis included logistic regression models and linear mixed model analysis. 
      RESULTS: Of the 155 patients with joint/back pain, 13 had chronic back pain, 80 
      peripheral joint complaints, and 62 axial and peripheral joint complaints. 
      Smoking, female gender, and IBD disease activity were independently associated 
      with IBD joint/back pain. The Assessment in Spondyloarthritis International 
      Society criteria for axial and peripheral SpA were fulfilled in 12.3% of 
      patients, with 9.7% [n = 15] receiving a rheumatological diagnosis of arthritis. 
      During the 12-month follow-up, the majority of the patients reporting joint/back 
      pain remained stable. CONCLUSIONS: In our cohort, the majority of IBD patients 
      reported joint/back pain and SpA was relatively common. To facilitate effective 
      care, gastroenterologists should be aware of the various features of SpA to 
      classify joint complaints and, by making use of an efficient referral algorithm, 
      to refer CBP patients to the rheumatologist.
CI  - Copyright (c) 2015 European Crohn's and Colitis Organisation (ECCO). Published by 
      Oxford University Press. All rights reserved. For permissions, please email: 
      journals.permissions@oup.com.
FAU - van Erp, S J
AU  - van Erp SJ
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands.
FAU - Brakenhoff, L K
AU  - Brakenhoff LK
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands.
FAU - van Gaalen, F A
AU  - van Gaalen FA
AD  - Department of Rheumatology, Leiden University Medical Center, Leiden, The 
      Netherlands.
FAU - van den Berg, R
AU  - van den Berg R
AD  - Department of Rheumatology, Leiden University Medical Center, Leiden, The 
      Netherlands.
FAU - Fidder, H H
AU  - Fidder HH
AD  - Department of Gastroenterology and Hepatology , University Medical Center 
      Utrecht, Utrecht, The Netherlands.
FAU - Verspaget, H W
AU  - Verspaget HW
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands.
FAU - Huizinga, T W
AU  - Huizinga TW
AD  - Department of Rheumatology, Leiden University Medical Center, Leiden, The 
      Netherlands.
FAU - Veenendaal, R A
AU  - Veenendaal RA
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands.
FAU - Wolterbeek, R
AU  - Wolterbeek R
AD  - Department of Medical Statistics, Leiden University Medical Center, Leiden, The 
      Netherlands.
FAU - van der Heijde, D
AU  - van der Heijde D
AD  - Department of Rheumatology, Leiden University Medical Center, Leiden, The 
      Netherlands.
FAU - van der Meulen-de Jong, A E
AU  - van der Meulen-de Jong AE
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands ae.meulen@lumc.nl.
FAU - Hommes, D W
AU  - Hommes DW
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands Center for Inflammatory Bowel Diseases, University of 
      California Los Angeles, Los Angeles, CA, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20151028
PL  - England
TA  - J Crohns Colitis
JT  - Journal of Crohn's & colitis
JID - 101318676
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
CIN - Nat Rev Gastroenterol Hepatol. 2016 Jan;13(1):9-10. PMID: 26669763
MH  - Adult
MH  - Back Pain/diagnosis/epidemiology/*etiology
MH  - C-Reactive Protein/*metabolism
MH  - Chronic Pain
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Incidence
MH  - Inflammatory Bowel Diseases/blood/*complications/diagnosis
MH  - Joint Diseases/diagnosis/epidemiology/*etiology
MH  - Male
MH  - Netherlands/epidemiology
MH  - Pain Measurement/*methods
MH  - Prospective Studies
MH  - Self Report
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Time Factors
OTO - NOTNLM
OT  - Crohn's disease
OT  - Inflammatory bowel disease
OT  - arthropathy
OT  - spondyloarthritis
OT  - ulcerative colitis
EDAT- 2015/10/30 06:00
MHDA- 2016/11/02 06:00
CRDT- 2015/10/30 06:00
PHST- 2015/07/09 00:00 [received]
PHST- 2015/10/13 00:00 [accepted]
PHST- 2015/10/30 06:00 [entrez]
PHST- 2015/10/30 06:00 [pubmed]
PHST- 2016/11/02 06:00 [medline]
AID - jjv195 [pii]
AID - 10.1093/ecco-jcc/jjv195 [doi]
PST - ppublish
SO  - J Crohns Colitis. 2016 Feb;10(2):166-75. doi: 10.1093/ecco-jcc/jjv195. Epub 2015 
      Oct 28.