PMID- 26512343
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151029
LR  - 20220321
IS  - 2211-4599 (Print)
IS  - 2211-4599 (Electronic)
IS  - 2211-4599 (Linking)
VI  - 9
DP  - 2015
TI  - Clinical outcomes after treatment with disc prostheses in three lumbar segments 
      compared to one- or two segments.
PG  - 49
LID - 10.14444/2049 [doi]
LID - 49
AB  - BACKGROUND: Fusion surgery in the rare patients suffering from symptomatic 
      degenerative disc disease (DDD) at three segments has been reported to produce 
      poor results and a high frequency of complications, why patients suffering from 
      DDD at three segments are seldom offered surgical treatment. PURPOSE: To compare 
      clinical outcome after one- and two years, between patients that have undergone 
      disc replacement surgery (TDR) at three segments and patients that have been 
      treated at less segments. METHODS: The present study is based on data recorded in 
      the Swedish Spine Registry (SweSpine). The study group consisted of 30 patients 
      who underwent three-segment TDR, the comparative group of 700 patients treated in 
      one or two segments. Analyses included comparisons of preoperative data, 
      postoperative results and improvement from baseline. RESULTS: Our results showed 
      no differences in outcome between groups at one- and two years postoperatively. 
      Improvements achieved after surgery in both groups well exceeded established 
      values for minimally clinically important difference (MCID). CONCLUSIONS: The 
      results of this study show that patients with a diagnosis of therapy-resistant 
      chronic low back pain (CLBP) due to DDD in one, two or even three lumbar segments 
      achieve similar and good results after TDR surgery. CLINICAL RELEVANCE: The rare 
      patients with severe and convincing DDD from three segments might in carefully 
      selected cases be offered surgery, with a reasonable chance of a beneficial 
      outcome.
FAU - Berg, Svante
AU  - Berg S
AD  - Stockholm Spine Center, Lowenstromska Hospital, Stockholm, Sweden.
FAU - Gillberg-Aronsson, Nina
AU  - Gillberg-Aronsson N
AD  - Medical School, Karolinska Institutet, Stockholm, Sweden.
LA  - eng
PT  - Journal Article
DEP - 20150930
PL  - Netherlands
TA  - Int J Spine Surg
JT  - International journal of spine surgery
JID - 101579005
PMC - PMC4610321
OTO - NOTNLM
OT  - Low Back Pain
OT  - disc degeneration
OT  - register study
OT  - three segments
OT  - total disc replacement
OT  - treatment outcome
EDAT- 2015/10/30 06:00
MHDA- 2015/10/30 06:01
PMCR- 2015/09/30
CRDT- 2015/10/30 06:00
PHST- 2015/10/30 06:00 [entrez]
PHST- 2015/10/30 06:00 [pubmed]
PHST- 2015/10/30 06:01 [medline]
PHST- 2015/09/30 00:00 [pmc-release]
AID - 14444-2049 [pii]
AID - 10.14444/2049 [doi]
PST - epublish
SO  - Int J Spine Surg. 2015 Sep 30;9:49. doi: 10.14444/2049. eCollection 2015.