PMID- 26515901
OWN - NLM
STAT- MEDLINE
DCOM- 20160906
LR  - 20151208
IS  - 1873-1244 (Electronic)
IS  - 0899-9007 (Linking)
VI  - 32
IP  - 1
DP  - 2016 Jan
TI  - Simplifications of the mini nutritional assessment short-form are predictive of 
      mortality among hospitalized young and middle-aged adults.
PG  - 95-100
LID - S0899-9007(15)00335-4 [pii]
LID - 10.1016/j.nut.2015.07.017 [doi]
AB  - OBJECTIVE: Measuring malnutrition in hospitalized patients is difficult in all 
      settings. I evaluated associations of items in the mini nutritional assessment 
      short-form (MNA-sf), a nutritional-risk screening tool previously validated in 
      the elderly, with malnutrition among hospitalized patients in Uganda. I used 
      results to construct two simplifications of this tool that may be applicable to 
      young and middle-aged adults. METHODS: I assessed the association of each MNA-sf 
      item with the mid-upper arm circumference (MUAC), a specific measure of 
      malnutrition at appropriate cut-offs. I incorporated only malnutrition-specific 
      items into the proposed simplifications scoring each item according to its 
      association with malnutrition. I assessed numbers classified to different 
      score-levels by the simplifications and, via proportional hazards regression, how 
      the simplifications predicted in-hospital mortality. RESULTS: I analyzed 318 
      patients (median age 37, interquartile range 27 to 56). Variables making it into 
      the simplifications were: reduced food intake, weight loss, mobility, and either 
      BMI in kg/m(2) (categorized as <16, 16 to 16.9, and >/=17) or MUAC in centimeters 
      (categorized as <16 or <17, 16 to 18.9 or 17 to 19.9, and >/=19 or >/=20 for females 
      and males respectively). Compared to the traditional MNA-sf, the simplifications 
      classified fewer patients as malnourished, yet remained strongly predictive of 
      in-hospital mortality. In the MUAC-incorporating simplification, malnourished 
      patients had 3.8-fold (95% CI 1.9 to 7.8) higher risk of in-hospital death than 
      those not malnourished; adjusting for age, sex, and HIV status. CONCLUSION: The 
      MNA-sf simplifications described may provide an improved measure of malnutrition 
      in hospitalized young and middle-aged adults.
CI  - Copyright (c) 2016 Elsevier Inc. All rights reserved.
FAU - Asiimwe, Stephen B
AU  - Asiimwe SB
AD  - Department of Medicine, Mbarara Regional Referral Hospital, Mbarara, Uganda; 
      Department of Epidemiology and Biostatistics, University of California San 
      Francisco, CA, USA. Electronic address: asiimwesteve@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20150903
PL  - United States
TA  - Nutrition
JT  - Nutrition (Burbank, Los Angeles County, Calif.)
JID - 8802712
SB  - IM
MH  - Adult
MH  - Female
MH  - Hospital Mortality
MH  - *Hospitalization
MH  - Humans
MH  - Male
MH  - Malnutrition/*diagnosis
MH  - Middle Aged
MH  - *Nutrition Assessment
OTO - NOTNLM
OT  - Hospitalized patients
OT  - MNA-sf
OT  - Malnutrition
OT  - Mini nutritional assessment
OT  - Young adults
EDAT- 2015/10/31 06:00
MHDA- 2016/09/07 06:00
CRDT- 2015/10/31 06:00
PHST- 2015/04/09 00:00 [received]
PHST- 2015/07/12 00:00 [revised]
PHST- 2015/07/30 00:00 [accepted]
PHST- 2015/10/31 06:00 [entrez]
PHST- 2015/10/31 06:00 [pubmed]
PHST- 2016/09/07 06:00 [medline]
AID - S0899-9007(15)00335-4 [pii]
AID - 10.1016/j.nut.2015.07.017 [doi]
PST - ppublish
SO  - Nutrition. 2016 Jan;32(1):95-100. doi: 10.1016/j.nut.2015.07.017. Epub 2015 Sep 
      3.