PMID- 26523024 OWN - NLM STAT- MEDLINE DCOM- 20161114 LR - 20181202 IS - 1499-2752 (Electronic) IS - 0315-162X (Linking) VI - 43 IP - 1 DP - 2016 Jan TI - CanVasc Recommendations for the Management of Antineutrophil Cytoplasm Antibody-associated Vasculitides. PG - 97-120 LID - 10.3899/jrheum.150376 [doi] AB - OBJECTIVE: The Canadian Vasculitis research network (CanVasc) is composed of physicians from different medical specialties and researchers with expertise in vasculitis. One of its aims is to develop recommendations for the diagnosis and management of antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV) in Canada. METHODS: Diagnostic and therapeutic questions were developed based on the results of a national needs assessment survey. A systematic review of existing non-Canadian recommendations and guidelines for the diagnosis and management of AAV and studies of AAV published after the 2009 European League Against Rheumatism/European Vasculitis Society recommendations (publication date: January 2009) until November 2014 was performed in the Medline database, Cochrane library, and main vasculitis conference proceedings. Quality of supporting evidence for each therapeutic recommendation was graded. The full working group as well as additional reviewers, including patients, reviewed the developed therapeutic recommendations and nontherapeutic statements using a modified 2-step Delphi technique and through discussion to reach consensus. RESULTS: Nineteen recommendations and 17 statements addressing general AAV diagnosis and management were developed, as well as appendices for practical use, for rheumatologists, nephrologists, respirologists, general internists, and all other healthcare professionals more occasionally involved in the management of patients with AAV in community and academic practice settings. CONCLUSION: These recommendations were developed based on a synthesis of existing international guidelines, other published supporting evidence, and expert consensus considering the Canadian healthcare context, with the intention of promoting best practices and improving healthcare delivery for patients with AAV. FAU - McGeoch, Lucy AU - McGeoch L AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Twilt, Marinka AU - Twilt M AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Famorca, Leilani AU - Famorca L AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Bakowsky, Volodko AU - Bakowsky V AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Barra, Lillian AU - Barra L AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Benseler, Susan M AU - Benseler SM AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Cabral, David A AU - Cabral DA AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Carette, Simon AU - Carette S AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Cox, Gerald P AU - Cox GP AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Dhindsa, Navjot AU - Dhindsa N AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Dipchand, Christine S AU - Dipchand CS AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Fifi-Mah, Aurore AU - Fifi-Mah A AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Goulet, Michelle AU - Goulet M AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Khalidi, Nader AU - Khalidi N AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Khraishi, Majed M AU - Khraishi MM AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Liang, Patrick AU - Liang P AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Milman, Nataliya AU - Milman N AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Pineau, Christian A AU - Pineau CA AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Reich, Heather N AU - Reich HN AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Samadi, Nooshin AU - Samadi N AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Shojania, Kam AU - Shojania K AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Taylor-Gjevre, Regina AU - Taylor-Gjevre R AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Towheed, Tanveer E AU - Towheed TE AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Trudeau, Judith AU - Trudeau J AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Walsh, Michael AU - Walsh M AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Yacyshyn, Elaine AU - Yacyshyn E AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, FAU - Pagnoux, Christian AU - Pagnoux C AD - From the Department of Rheumatology, Mount Sinai Hospital, University of Toronto; Division of Nephrology, University Health Network, Toronto; Division of Rheumatology, Division of Respirology, and Department of Medicine and Department of Clinical Epidemiology and Biostatistics, McMaster University, St. Joseph's Healthcare, Hamilton; Division of Rheumatology, St. Joseph's Health Care, London; Langs Community Centre, Cambridge; Division of Rheumatology, the Ottawa Hospital/University of Ottawa, Ottawa; Division of Rheumatology and the Arthritis Program Research Group in Newmarket, Newmarket; Department of Medicine, Queen's University, Kingston, Ontario; Division of Pediatric Rheumatology, Alberta Children's Hospital, and Division of Rheumatology, University of Calgary, Calgary; Division of Rheumatology, University of Alberta, Edmonton, Alberta; Division of Rheumatology, QEII Health Sciences Centre and Dalhousie University; Division of Nephrology, Dalhousie University, Halifax, Nova Scotia; Division of Pediatric Rheumatology, BC Children's Hospital and University of British Columbia; Division of Rheumatology, Arthritis Research Canada, University of British Columbia, Vancouver, British Columbia; Section of Rheumatology, University of Manitoba, Arthritis Centre, Winnipeg, Manitoba; Division of Internal Medicine, Hopital Du Sacre-Coeur; Division of Rheumatology, Lupus and Vasculitis clinic, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke; Division of Rheumatology, CHAU Hotel-Dieu de Levis, Universite Laval, Quebec City, Quebec; Division of Rheumatology, Memorial University of Newfoundland, Nexus Clinical Research, St. John's, Newfoundland; Division of Rheumatology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.L. McGeoch, MD, Department of Rheumatology, Mount Sinai Hospital, University of Toronto, currently: Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK; M. Twilt, CN - Canadian Vasculitis Research Network LA - eng PT - Consensus Development Conference PT - Journal Article PT - Review PT - Systematic Review DEP - 20151101 PL - Canada TA - J Rheumatol JT - The Journal of rheumatology JID - 7501984 SB - IM MH - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*diagnosis/*therapy MH - Canada MH - Delphi Technique MH - Disease Management MH - Evidence-Based Medicine MH - Female MH - Humans MH - Male MH - *Practice Guidelines as Topic OTO - NOTNLM OT - ANCA-ASSOCIATED VASCULITIS OT - CONSENSUS DEVELOPMENT CONFERENCE OT - DRUG THERAPY OT - PRACTICE GUIDELINES OT - QUALITY OF HEALTHCARE OT - VASCULITIS EDAT- 2015/11/03 06:00 MHDA- 2016/11/15 06:00 CRDT- 2015/11/03 06:00 PHST- 2015/07/28 00:00 [accepted] PHST- 2015/11/03 06:00 [entrez] PHST- 2015/11/03 06:00 [pubmed] PHST- 2016/11/15 06:00 [medline] AID - jrheum.150376 [pii] AID - 10.3899/jrheum.150376 [doi] PST - ppublish SO - J Rheumatol. 2016 Jan;43(1):97-120. doi: 10.3899/jrheum.150376. Epub 2015 Nov 1.