PMID- 26523845
OWN - NLM
STAT- MEDLINE
DCOM- 20170228
LR  - 20200319
IS  - 1542-474X (Electronic)
IS  - 1082-720X (Print)
IS  - 1082-720X (Linking)
VI  - 21
IP  - 4
DP  - 2016 Jul
TI  - The Value of Lead aVR ST Segment Changes in Localizing Culprit Lesion in Acute 
      Inferior Myocardial Infarction and Its Prognostic Impact.
PG  - 389-96
LID - 10.1111/anec.12324 [doi]
AB  - BACKGROUND: Identifying infarct-related artery (IRA) in patients with inferior ST 
      elevation myocardial infarction (STEMI) has prognostic and therapeutic benefits. 
      OBJECTIVES: To differentiate IRA and the location of culprit lesion in inferior 
      STEMI, using ST segment changes in lead aVR. METHODS: ST segment changes in lead 
      aVR were recorded in 150 patients, admitted with first inferior STEMI. The 
      association of IRA and the location of culprit lesion with ST segment changes in 
      aVR were investigated. RESULTS: ST elevation >/= 0.5 mm in lead aVR was present in 
      17 patients (11.3%), ST depression >/= 0.5 mm in 74 patients (49.3%) and 59 
      patients (39.3%) did not have significant ST segment changes. Right coronary 
      artery (RCA) was the IRA in 117 patients (78%) and left circumflex artery (LCX) 
      in 33 patients (22%). Prevalence of RCA involvement as the IRA was different in 
      three study groups (94.1% in ST elevation group, 83.1% in isoelectric group and 
      70.3% in ST depression group, P = 0.049). Presence of ST elevation had a 
      sensitivity and specificity of 13.68 % and 96.97%, for detecting RCA lesions, 
      respectively. ST depression had 66.67% sensitivity and 55.56% specificity for 
      identifying LCX lesions. Clinical complications were low in our study with no 
      significant difference among patients of three groups. CONCLUSIONS: Presence of 
      ST elevation is highly suggestive of RCA lesions versus LCX lesions, whereas 
      absence of ST elevation cannot rule out RCA lesions. Presence of ST depression 
      has a moderate sensitivity and specificity for LCX lesions.
CI  - (c) 2015 Wiley Periodicals, Inc.
FAU - Pourafkari, Leili
AU  - Pourafkari L
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Tajlil, Arezou
AU  - Tajlil A
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Mahmoudi, Seyed Sajjad
AU  - Mahmoudi SS
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Ghaffari, Samad
AU  - Ghaffari S
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
LA  - eng
PT  - Journal Article
DEP - 20151102
PL  - United States
TA  - Ann Noninvasive Electrocardiol
JT  - Annals of noninvasive electrocardiology : the official journal of the 
      International Society for Holter and Noninvasive Electrocardiology, Inc
JID - 9607443
RN  - 0 (Biomarkers)
SB  - IM
MH  - Biomarkers/blood
MH  - Electrocardiography/*methods
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Inferior Wall Myocardial Infarction/*diagnosis/mortality/pathology/therapy
MH  - Male
MH  - Middle Aged
MH  - Percutaneous Coronary Intervention
MH  - Prognosis
MH  - Prospective Studies
MH  - Risk Factors
MH  - Sensitivity and Specificity
MH  - Thrombolytic Therapy
MH  - Treatment Outcome
PMC - PMC6931787
OTO - NOTNLM
OT  - acute inferior myocardial infarction
OT  - coronary angiography
OT  - electrocardiography
EDAT- 2015/11/03 06:00
MHDA- 2017/03/01 06:00
PMCR- 2015/11/02
CRDT- 2015/11/03 06:00
PHST- 2015/11/03 06:00 [entrez]
PHST- 2015/11/03 06:00 [pubmed]
PHST- 2017/03/01 06:00 [medline]
PHST- 2015/11/02 00:00 [pmc-release]
AID - ANEC12324 [pii]
AID - 10.1111/anec.12324 [doi]
PST - ppublish
SO  - Ann Noninvasive Electrocardiol. 2016 Jul;21(4):389-96. doi: 10.1111/anec.12324. 
      Epub 2015 Nov 2.