PMID- 26536986
OWN - NLM
STAT- MEDLINE
DCOM- 20160201
LR  - 20181023
IS  - 1016-5169 (Print)
IS  - 1016-5169 (Linking)
VI  - 43
IP  - 7
DP  - 2015 Oct
TI  - Relationship between red cell distribution width and contrast-induced nephropathy 
      in patients who underwent primary percutaneous coronary intervention.
PG  - 613-20
LID - 10.5543/tkda.2015.37941 [doi]
AB  - OBJECTIVE: This study evaluated the relationship between contrast-induced 
      nephropathy (CIN) and red cell distribution width (RDW) in patients who underwent 
      primary percutaneous coronary intervention (PCI). METHODS: A total of 359 
      patients with ST elevation myocardial infarction (STEMI) who had undergone 
      primary PCI were included in the study. An increase of 25% in serum creatinine 
      value after 48 h, or an increase of >0.5 mg/dL in the basal value was defined as 
      CIN. RESULTS: Of the patients included in the study, 49 (13.8%) developed CIN. 
      Compared to the CIN-negative group, CIN-positive patients had increased RDW 
      values (16.9 +/- 2.00 and 14.8 +/- 2.14 respectively, p<0.001). The latter were also 
      older patients, and had increased age rates of diabetes mellitus, baseline 
      creatinine, ∆-creatinine and amount of contrast media were higher and left 
      ventricular ejection fraction and baseline glomerular filtration rate (GFR) were 
      lower in the CIN-positive group than in the CIN-negative group. A statistically 
      weak correlation was found between RDW and change in creatinine levels 
      (∆-creatinine) (r=0.250, p=0.002). Diabetes mellitus (odds ratio [OR]: 3.252, 95% 
      CI=1.184-8.951, p=0.022), high RDW (OR: 1.716, 95% CI=1.363-2.157, p<0.001), 
      baseline low GFR (OR: 0.941, 95% CI=0.925-0.971, p<0.001), ∆-creatinine (OR: 
      1.197, 95% CI=1.061-2.986, p=0.006) and increased amount of contrast media (OR: 
      1.187, 95% CI=1.048-3.02, p=0.001) used were observed as independent predictors 
      of CIN. CONCLUSION: The study found diabetes mellitus, high RDW, basal low GFR, 
      ∆-creatinine and increased contrast amount used to be the independent predictors 
      of CIN in STEMI patients who underwent PCI.
FAU - Akkoyun, Dursun Cayan
AU  - Akkoyun DC
AD  - Department of Cardiology, Namik Kemal University Faculty of Medicine, Tekirdag, 
      Turkey.
FAU - Akyuz, Aydin
AU  - Akyuz A
AD  - Department of Cardiology, Namik Kemal University Faculty of Medicine, Tekirdag, 
      Turkey.
FAU - Kurt, Omer
AU  - Kurt O
AD  - Department of Urology, Namik Kemal University Faculty of Medicine, Tekirdag, 
      Turkey.
FAU - Bilir, Bulent
AU  - Bilir B
AD  - Department of Internal Medicine, Namik Kemal University Faculty of Medicine, 
      Tekirdag, Turkey.
FAU - Alpsoy, Seref
AU  - Alpsoy S
AD  - Department of Cardiology, Namik Kemal University Faculty of Medicine, Tekirdag, 
      Turkey.
FAU - Guler, Niyazi
AU  - Guler N
AD  - Department of Cardiology, Namik Kemal University Faculty of Medicine, Tekirdag, 
      Turkey.
LA  - eng
PT  - Journal Article
PL  - Turkey
TA  - Turk Kardiyol Dern Ars
JT  - Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
JID - 9426239
RN  - 0 (Contrast Media)
SB  - IM
CIN - Angiology. 2016 Jul;67(6):598. doi: 10.1177/0003319715623398. PMID: 26685179
CIN - Turk Kardiyol Dern Ars. 2016 Mar;44(2):189. doi: 10.5543/tkda.2016.34280. PMID: 
      27111325
CIN - Turk Kardiyol Dern Ars. 2016 Mar;44(2):190-1. doi: 10.5543/tkda.2016.35040. PMID: 
      27111327
MH  - Adult
MH  - Aged
MH  - Contrast Media/*adverse effects
MH  - Erythrocyte Indices
MH  - Female
MH  - Humans
MH  - Kidney Diseases/blood/chemically induced/*etiology
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*therapy
MH  - Percutaneous Coronary Intervention/adverse effects
MH  - Postoperative Complications/blood/*etiology
MH  - ROC Curve
MH  - Radiography, Interventional/adverse effects
EDAT- 2015/11/06 06:00
MHDA- 2016/02/02 06:00
CRDT- 2015/11/06 06:00
PHST- 2015/11/06 06:00 [entrez]
PHST- 2015/11/06 06:00 [pubmed]
PHST- 2016/02/02 06:00 [medline]
AID - 10.5543/tkda.2015.37941 [doi]
PST - ppublish
SO  - Turk Kardiyol Dern Ars. 2015 Oct;43(7):613-20. doi: 10.5543/tkda.2015.37941.