PMID- 26538716 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20151105 LR - 20220318 IS - 1998-3611 (Electronic) IS - 0019-5154 (Print) IS - 0019-5154 (Linking) VI - 60 IP - 5 DP - 2015 Sep-Oct TI - Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases. PG - 519 LID - 10.4103/0019-5154.164412 [doi] AB - BACKGROUND: Atopic dermatitis is a distinct age-related clinical entity. Its etiopathogenesis is largely insubstantial. Nevertheless, it seems to be an outcome of interplay of maternal and inheritance, pregnancy/intrauterine and environmental factors. Besides, immune dysregulation, and nutritional supplements also play essential roles. Its diagnosis has been perpetuated by three or more major/minor criteria. OBJECTIVES: An endeavor to study its demographic and clinical pattern in contemporary prospective. MATERIALS AND METHODS: 100 fresh patients of atopic dermatitis, diagnosed on the basis of an established three or more major and minor criteria, salient presentations of which were recorded in a preset proforma, which also recorded age, duration, age of onset, and sex. Serum immunoglobulin E (IgE) levels were determined by conventional technique. The data thus obtained was analysed to study its clinical pattern and to correlate its severity to IgE levels. RESULTS: Its overall (new and old) prevalence was 0.98%, while that of new patients was 0.24%. 83 (83%) were in the age group of 2-12 years, of which 54 (83.1%) were males and 29 (82.9%) were female, of which 70 (70%) had urban, while 30 (30%) had rural background. Its duration varied from 8 to 192 weeks, with a mean of 76 weeks, and a standard deviation of 21.42 weeks [76 +/- 21.42]. CONCLUSION: Atopic dermatitis is a discrete, overt, age and IgE-related entity frequently displaying varying demographic and clinical connotation. FAU - Sehgal, Virendra N AU - Sehgal VN AD - Dermato Venereology (Skin/VD) Center, Sehgal Nursing Home, Panchwati, Delhi, India. FAU - Srivastava, Govind AU - Srivastava G AD - Skin Institute, School of Dermatology, Greater Kailash, New Delhi, India. FAU - Aggarwal, Ashok K AU - Aggarwal AK AD - Skin Institute, School of Dermatology, Greater Kailash, New Delhi, India. FAU - Saxena, Deepti AU - Saxena D AD - Skin Institute, School of Dermatology, Greater Kailash, New Delhi, India. FAU - Chatterjee, Kingshuk AU - Chatterjee K AD - Department of Dermatology, Bankura Sammilani Medical College, Bankura, West Bengal, India. FAU - Khurana, Ananta AU - Khurana A AD - Department of Dermatology, Dr RML hospital and Postgraduate Institute of Medical Education and research (PGIMER), New Delhi, India. LA - eng PT - Journal Article PL - India TA - Indian J Dermatol JT - Indian journal of dermatology JID - 0370750 PMC - PMC4601437 OTO - NOTNLM OT - Atopic Dermatitis OT - immunoglobulin IgE OT - prospective cross-sectional COIS- Conflict of Interest: Nil. EDAT- 2015/11/06 06:00 MHDA- 2015/11/06 06:01 PMCR- 2015/09/01 CRDT- 2015/11/06 06:00 PHST- 2015/11/06 06:00 [entrez] PHST- 2015/11/06 06:00 [pubmed] PHST- 2015/11/06 06:01 [medline] PHST- 2015/09/01 00:00 [pmc-release] AID - IJD-60-519d [pii] AID - 10.4103/0019-5154.164412 [doi] PST - ppublish SO - Indian J Dermatol. 2015 Sep-Oct;60(5):519. doi: 10.4103/0019-5154.164412.