PMID- 26545916
OWN - NLM
STAT- MEDLINE
DCOM- 20160713
LR  - 20181202
IS  - 1753-4887 (Electronic)
IS  - 0029-6643 (Linking)
VI  - 74
IP  - 1
DP  - 2016 Jan
TI  - Involvement of dietary saturated fats, from all sources or of dairy origin only, 
      in insulin resistance and type 2 diabetes.
PG  - 33-47
LID - 10.1093/nutrit/nuv043 [doi]
AB  - Reducing the consumption of saturated fatty acids to a level as low as possible 
      is a European public health recommendation to reduce the risk of cardiovascular 
      disease. The association between dietary intake of saturated fatty acids and 
      development and management of type 2 diabetes mellitus (T2DM), however, is a 
      matter of debate. A literature search was performed to identify prospective 
      studies and clinical trials in humans that explored the association between 
      dietary intake of saturated fatty acids and risk of insulin resistance and T2DM. 
      Furthermore, to assess whether specific foods, and not just the saturated fatty 
      acid content of the food matrix, can have differential effects on human health, 
      the relationship between consumption of full-fat dairy products, a main source of 
      dietary saturated fatty acids, and risk of insulin resistance and T2DM was 
      studied. There is no evidence that dietary saturated fatty acids from varied food 
      sources affect the risk of insulin resistance or T2DM, nor is intake of full-fat 
      dairy products associated with this risk. These findings strongly suggest that 
      future studies on the effects of dietary saturated fatty acids should take into 
      account the complexity of the food matrix. Furthermore, communication on 
      saturated fats and their health effects should be prudent and well informed.
CI  - (c) The Author(s) 2015. Published by Oxford University Press on behalf of the 
      International Life Sciences Institute. All rights reserved. For Permissions, 
      please e-mail: journals.permissions@oup.com.
FAU - Morio, Beatrice
AU  - Morio B
AD  - B. Morio is with the CarMeN Laboratory (Inserm 1060, INRA 1397, INSA), University 
      of Lyon, Faculty of Medicine Lyon - South, Oullins, France. B. Morio and A. 
      Fardet are with the French National Institute for Agricultural Research (INRA), 
      UMR1019 Human Nutrition, Center for Human Nutrition Research (CRNH) Auvergne, 
      Clermont-Ferrand, France. P. Legrand is with the Biochemistry and Human Nutrition 
      Laboratory, Agrocampus - French National Institute for Agricultural Research 
      (INRA), Rennes, France. J-M. Lecerf is with the Nutrition Department, Pasteur 
      Institute of Lille, Lille, France. beatrice.morio@lyon.inra.fr.
FAU - Fardet, Anthony
AU  - Fardet A
AD  - B. Morio is with the CarMeN Laboratory (Inserm 1060, INRA 1397, INSA), University 
      of Lyon, Faculty of Medicine Lyon - South, Oullins, France. B. Morio and A. 
      Fardet are with the French National Institute for Agricultural Research (INRA), 
      UMR1019 Human Nutrition, Center for Human Nutrition Research (CRNH) Auvergne, 
      Clermont-Ferrand, France. P. Legrand is with the Biochemistry and Human Nutrition 
      Laboratory, Agrocampus - French National Institute for Agricultural Research 
      (INRA), Rennes, France. J-M. Lecerf is with the Nutrition Department, Pasteur 
      Institute of Lille, Lille, France.
FAU - Legrand, Philippe
AU  - Legrand P
AD  - B. Morio is with the CarMeN Laboratory (Inserm 1060, INRA 1397, INSA), University 
      of Lyon, Faculty of Medicine Lyon - South, Oullins, France. B. Morio and A. 
      Fardet are with the French National Institute for Agricultural Research (INRA), 
      UMR1019 Human Nutrition, Center for Human Nutrition Research (CRNH) Auvergne, 
      Clermont-Ferrand, France. P. Legrand is with the Biochemistry and Human Nutrition 
      Laboratory, Agrocampus - French National Institute for Agricultural Research 
      (INRA), Rennes, France. J-M. Lecerf is with the Nutrition Department, Pasteur 
      Institute of Lille, Lille, France.
FAU - Lecerf, Jean-Michel
AU  - Lecerf JM
AD  - B. Morio is with the CarMeN Laboratory (Inserm 1060, INRA 1397, INSA), University 
      of Lyon, Faculty of Medicine Lyon - South, Oullins, France. B. Morio and A. 
      Fardet are with the French National Institute for Agricultural Research (INRA), 
      UMR1019 Human Nutrition, Center for Human Nutrition Research (CRNH) Auvergne, 
      Clermont-Ferrand, France. P. Legrand is with the Biochemistry and Human Nutrition 
      Laboratory, Agrocampus - French National Institute for Agricultural Research 
      (INRA), Rennes, France. J-M. Lecerf is with the Nutrition Department, Pasteur 
      Institute of Lille, Lille, France.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20151105
PL  - United States
TA  - Nutr Rev
JT  - Nutrition reviews
JID - 0376405
RN  - 0 (Dietary Fats)
RN  - 0 (Fatty Acids)
SB  - IM
MH  - *Dairy Products
MH  - *Diabetes Mellitus, Type 2/etiology
MH  - *Diet
MH  - Dietary Fats/*pharmacology
MH  - Fatty Acids/*pharmacology
MH  - Humans
MH  - *Insulin Resistance
OTO - NOTNLM
OT  - human
OT  - lipid nutrition
OT  - prevention of diabetes
OT  - public health
OT  - saturated fatty acids
EDAT- 2015/11/08 06:00
MHDA- 2016/07/14 06:00
CRDT- 2015/11/08 06:00
PHST- 2015/11/08 06:00 [entrez]
PHST- 2015/11/08 06:00 [pubmed]
PHST- 2016/07/14 06:00 [medline]
AID - nuv043 [pii]
AID - 10.1093/nutrit/nuv043 [doi]
PST - ppublish
SO  - Nutr Rev. 2016 Jan;74(1):33-47. doi: 10.1093/nutrit/nuv043. Epub 2015 Nov 5.