PMID- 26551429
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 0236-6290 (Print)
IS  - 0236-6290 (Linking)
VI  - 63
IP  - 3
DP  - 2015 Sep
TI  - Serum inoculation as a possibility for elimination of porcine reproductive and 
      respiratory syndrome (PRRS) from a farrow-to-finish pig farm.
PG  - 389-99
LID - 10.1556/004.2015.037 [doi]
AB  - The large heterogeneity among porcine reproductive and respiratory syndrome virus 
      (PRRSV) isolates is probably the main obstacle to its effective control using 
      current commercial vaccines. Intentionally exposing all breeding pigs to PRRSV 
      circulating on the farm could eliminate porcine reproductive and respiratory 
      syndrome (PRRS) from the herd. The objective of this study was to eliminate PRRS 
      from a farrow-to-finish pig farm by serum inoculation. The owner was acquainted 
      with the strict biosecurity measures. Breeding pigs were immunised with serum, 
      which was obtained from PRRSV-positive weaners from the same farm. The percent of 
      antibody high positive breeding pigs decreased six months after serum 
      inoculation, while 34 months after serum inoculation no more antibody high 
      positive pigs were detected and 56.8% of breeding pigs and all other categories 
      were free of antibodies. In the breeding herd no virus was detected during all 
      testing while PRRSV circulated in 2-month-old weaners until 12 months after serum 
      inoculation. Later all tested samples from weaners, growers and fatteners were 
      negative. Herd closure and the adoption of strict biosecurity measures are 
      essential. Serum inoculation of the breeding herd proved to be a successful 
      measure for eliminating PRRS from this farrow-to-finish farm.
FAU - Stukelj, Marina
AU  - Stukelj M
AD  - Institute for the Health Care of Pigs, University of Ljubljana , Gerbiceva 60, 
      1000 Ljubljana , Slovenia.
FAU - Plut, Jan
AU  - Plut J
AD  - Institute for the Health Care of Pigs, University of Ljubljana , Gerbiceva 60, 
      1000 Ljubljana , Slovenia.
FAU - Toplak, Ivan
AU  - Toplak I
AD  - Institute for Microbiology and Parasitology, Veterinary Faculty, University of 
      Ljubljana , Gerbiceva 60, 1000 Ljubljana , Slovenia.
LA  - eng
PT  - Journal Article
PL  - Hungary
TA  - Acta Vet Hung
JT  - Acta veterinaria Hungarica
JID - 8406376
SB  - IM
OTO - NOTNLM
OT  - PRRS
OT  - Porcine
OT  - elimination
OT  - immunisation
OT  - serum inoculation
EDAT- 2015/11/10 06:00
MHDA- 2015/11/10 06:01
CRDT- 2015/11/10 06:00
PHST- 2015/11/10 06:00 [entrez]
PHST- 2015/11/10 06:00 [pubmed]
PHST- 2015/11/10 06:01 [medline]
AID - 10.1556/004.2015.037 [doi]
PST - ppublish
SO  - Acta Vet Hung. 2015 Sep;63(3):389-99. doi: 10.1556/004.2015.037.