PMID- 26554324
OWN - NLM
STAT- MEDLINE
DCOM- 20160826
LR  - 20220330
IS  - 1538-1145 (Electronic)
IS  - 1527-4160 (Linking)
VI  - 21
IP  - 6
DP  - 2015 Nov
TI  - Quality of Sleep in Patients With Bipolar I Disorder During Remission.
PG  - 419-26
LID - 10.1097/PRA.0000000000000116 [doi]
AB  - BACKGROUND AND GOALS: Sleep disturbances have been noted not only during 
      affective episodes in bipolar disorder, but also between affective episodes. The 
      goal of this study was to assess and identify determinants of sleep quality in 
      patients with bipolar I disorder. METHODS: This cross-sectional study enrolled 
      patients with bipolar disorder who were currently in remission. Sleep quality was 
      assessed using the Pittsburgh Sleep Quality Index (PSQI). Mood symptoms were 
      evaluated using the Young Mania Rating Scale (YMRS) and the Hamilton Depression 
      Rating Scale (Ham-D). Adherence was assessed using the Medication Adherence 
      Rating Scale. RESULTS: The mean age in the sample (N=103) was 37.4 years; 44.7% 
      of the sample were men. On the basis of PSQI scores, 41 patients (39.8%) were 
      poor sleepers. Poor sleepers had significantly higher Ham-D scores (mean score of 
      1.8 vs. 0.9, P=0.012) and higher rates of medication nonadherence (36.6% vs. 
      11.3%, P=0.002). The relationship between Ham-D scores and sleep quality did not 
      remain significant when the sleep-related items on the Ham-D were removed. 
      Logistic regression analysis suggested that medication nonadherence was the only 
      independent predictor of poor sleep quality in this study. CONCLUSIONS: A 
      significant proportion of patients with bipolar disorder who are in remission 
      have sleep problems that seem to be independent of core symptoms of depression.
FAU - Karthick, Subramanian
AU  - Karthick S
AD  - KARTHICK, KATTIMANI, BHARADWAJ, and RAJKUMAR: Department of Psychiatry, 
      Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, 
      India SARKAR: Department of Psychiatry, Sree Balaji Medical College and Hospital, 
      Chromepet, Chennai, India.
FAU - Kattimani, Shivanand
AU  - Kattimani S
FAU - Sarkar, Siddharth
AU  - Sarkar S
FAU - Bharadwaj, Balaji
AU  - Bharadwaj B
FAU - Rajkumar, Ravi P
AU  - Rajkumar RP
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Psychiatr Pract
JT  - Journal of psychiatric practice
JID - 100901141
RN  - 0 (Psychotropic Drugs)
SB  - IM
MH  - Adult
MH  - *Bipolar Disorder/complications/diagnosis/physiopathology/therapy
MH  - *Depression/diagnosis/drug therapy
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Outcome Assessment, Health Care
MH  - Patient Compliance
MH  - Psychiatric Status Rating Scales
MH  - Psychotropic Drugs/*therapeutic use
MH  - Remission Induction
MH  - *Sleep Wake Disorders/diagnosis/etiology
EDAT- 2015/11/12 06:00
MHDA- 2016/08/27 06:00
CRDT- 2015/11/12 06:00
PHST- 2015/11/12 06:00 [entrez]
PHST- 2015/11/12 06:00 [pubmed]
PHST- 2016/08/27 06:00 [medline]
AID - 00131746-201511000-00004 [pii]
AID - 10.1097/PRA.0000000000000116 [doi]
PST - ppublish
SO  - J Psychiatr Pract. 2015 Nov;21(6):419-26. doi: 10.1097/PRA.0000000000000116.