PMID- 26558217
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151111
LR  - 20200930
IS  - 2222-3959 (Print)
IS  - 2227-4898 (Electronic)
IS  - 2222-3959 (Linking)
VI  - 8
IP  - 5
DP  - 2015
TI  - Fundus autofluorescence in central serous chorioretinopathy: association with 
      spectral-domain optical coherence tomography and fluorescein angiography.
PG  - 1003-7
LID - 10.3980/j.issn.2222-3959.2015.05.27 [doi]
AB  - AIM: To evaluate the correlation among changes in fundus autofluorescence (AF) 
      measured using infrared fundus AF (IR-AF) and short-wave length fundus AF (SW-AF) 
      with changes in spectral-domain optical coherence tomography (SD-OCT) and 
      fluorescein angiography (FA) in central serous chorioretinopathy (CSC). METHODS: 
      Two hundred and twenty consecutive patients with CSC were included. In addition 
      to AF, patients were assessed by means of SD-OCT and FA. Abnormalities in images 
      of IR-AF, SW-AF, FA were analyzed and correlated with the corresponding outer 
      retinal alterations in SD-OCT findings. RESULTS: Eyes with abnormalities on 
      either IR-AF or SW-AF were found in 256 eyes (58.18%), among them 256 eyes (100%) 
      showed abnormal IR-AF, but SW-AF abnormalities were present only in 213 eyes 
      (83.20%). The hypo-IR-AF corresponded to accumulation of sub-retinal liquid, 
      collapse of retinal pigment epithelium (RPE) or detachment of RPE with or without 
      RPE leakage point in the corresponding area. The hyper-IR-AF corresponded to the 
      area with loss of the ellipsoid portion of the inner segments and sub-sensory 
      retinal deposits or focal melanogenesis under sensory retina. The hypo-SW-AF 
      corresponded to accumulation of sub-retinal liquid or atrophy of RPE. The 
      hyper-SW-AF associated with sub-sensory retinal deposits, detachment of RPE and 
      focal melanogenesis. CONCLUSION: IR-AF was more sensitive than SW-AF and FA for 
      identifying pathological abnormalities in CSC. The characteristics of IR-AF in 
      CSC were attributable to the modification of melanin in the RPE. IR-AF should be 
      used as a common diagnostic tool for identifying pathological lesion in CSC.
FAU - Zhang, Peng
AU  - Zhang P
AD  - Department of Ophthalmology, Xijing Hospital, the Fourth Military Medical 
      University, Eye Institute of Chinese PLA, Xi'an 710032, Shaanxi Province, China.
FAU - Wang, Hai-Yan
AU  - Wang HY
AD  - Department of Ophthalmology, Xijing Hospital, the Fourth Military Medical 
      University, Eye Institute of Chinese PLA, Xi'an 710032, Shaanxi Province, China.
FAU - Zhang, Zi-Feng
AU  - Zhang ZF
AD  - Department of Ophthalmology, Xijing Hospital, the Fourth Military Medical 
      University, Eye Institute of Chinese PLA, Xi'an 710032, Shaanxi Province, China.
FAU - Sun, Dong-Jie
AU  - Sun DJ
AD  - Department of Ophthalmology, Xijing Hospital, the Fourth Military Medical 
      University, Eye Institute of Chinese PLA, Xi'an 710032, Shaanxi Province, China.
FAU - Zhu, Jin-Ting
AU  - Zhu JT
AD  - Department of Ophthalmology, Xijing Hospital, the Fourth Military Medical 
      University, Eye Institute of Chinese PLA, Xi'an 710032, Shaanxi Province, China.
FAU - Li, Juan
AU  - Li J
AD  - Department of Ophthalmology, Xijing Hospital, the Fourth Military Medical 
      University, Eye Institute of Chinese PLA, Xi'an 710032, Shaanxi Province, China.
FAU - Wang, Yu-Sheng
AU  - Wang YS
AD  - Department of Ophthalmology, Xijing Hospital, the Fourth Military Medical 
      University, Eye Institute of Chinese PLA, Xi'an 710032, Shaanxi Province, China.
LA  - eng
PT  - Journal Article
DEP - 20151018
PL  - China
TA  - Int J Ophthalmol
JT  - International journal of ophthalmology
JID - 101553860
PMC - PMC4630986
OTO - NOTNLM
OT  - central serous chorioretinopathy
OT  - fluorescein angiography
OT  - fundus autofluorescence
OT  - optical coherence tomography
EDAT- 2015/11/12 06:00
MHDA- 2015/11/12 06:01
PMCR- 2015/10/18
CRDT- 2015/11/12 06:00
PHST- 2014/09/09 00:00 [received]
PHST- 2014/12/26 00:00 [accepted]
PHST- 2015/11/12 06:00 [entrez]
PHST- 2015/11/12 06:00 [pubmed]
PHST- 2015/11/12 06:01 [medline]
PHST- 2015/10/18 00:00 [pmc-release]
AID - ijo-08-05-1003 [pii]
AID - 10.3980/j.issn.2222-3959.2015.05.27 [doi]
PST - epublish
SO  - Int J Ophthalmol. 2015 Oct 18;8(5):1003-7. doi: 
      10.3980/j.issn.2222-3959.2015.05.27. eCollection 2015.