PMID- 26559701
OWN - NLM
STAT- MEDLINE
DCOM- 20160810
LR  - 20191113
IS  - 1940-4344 (Electronic)
IS  - 1940-4344 (Linking)
VI  - 17
IP  - 7
DP  - 2015
TI  - In Vitro and In Vivo Antioxidant Effects of Polysaccharides from Nameko Medicinal 
      Mushroom, Pholiota nameko SW-01 (Higher Basidiomycetes).
PG  - 671-80
AB  - Extra- (EPS) and intracellular polysaccharides (IPS) from Pholiota nameko SW-01 
      were extracted, and in vitro and in vivo antioxidant effects were processed. 
      Briefly, the in vitro antioxidant results indicated that the inhibition effects 
      of IPS at a dose of 500 mg/L on superoxide anions, hydroxyl radicals, and 
      1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals were 63.24 +/- 1.12%, 53.11 +/- 2.92%, 
      and 59.33 +/- 9.37%, which were 7.70%, 14.84%, and 11.40% higher than those of EPS, 
      and 9.79%, 20.32%, and 4.59% higher than those of butylated hydroxytoluene (BHT), 
      respectively. The reducing power of IPS reached 0.593 +/- 0.21 (absorbance at 700 
      nm), which was 11.30% higher than that of EPS and 15.51% higher than that of BHT. 
      In vivo antioxidant results proved that both IPS and EPS significantly 
      upregulated the enzyme activities of superoxide dismutase (SOD), GSH peroxide 
      (GSH-Px), catalase (CAT), and alanine transaminase (ALT). In addition, glycosidic 
      bond types of EPS and IPS were primarily characterized. The findings indicate the 
      potential antioxidant effects of polysaccharide extract from Ph. Nameko. Thus, 
      this species has potential applicability as an antioxidant agent and should be 
      studied further.
FAU - Zhang, Jianjun
AU  - Zhang J
AD  - College of Life Science, Shandong Agricultural University, Taian, Shandong, 
      China.
FAU - Xu, Nuo
AU  - Xu N
AD  - College of Life Science, Shandong Agricultural University, Taian, Shandong, 
      China.
FAU - Wang, Guoyi
AU  - Wang G
AD  - College of Life Science, Shandong Agricultural University, Taian, Shandong, 
      China.
FAU - Zhao, Huajie
AU  - Zhao H
AD  - College of Life Science, Shandong Agricultural University, Taian, Shandong, 
      China.
FAU - Lin, Lin
AU  - Lin L
AD  - College of Life Science, Shandong Agricultural University, Taian, Shandong, 
      China.
FAU - Jia, Mengshi
AU  - Jia M
AD  - Second High School of Taian, Taian, Shandong, China.
FAU - Jia, Le
AU  - Jia L
AD  - College of Life Science, Shandong Agricultural University, Taian, Shandong, 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Med Mushrooms
JT  - International journal of medicinal mushrooms
JID - 100886202
RN  - 0 (Antioxidants)
RN  - 0 (Polysaccharides)
SB  - IM
MH  - Agaricales/*chemistry
MH  - Animals
MH  - Antioxidants/isolation & purification/*pharmacology
MH  - Fermentation
MH  - Mice
MH  - Polysaccharides/isolation & purification/*pharmacology
EDAT- 2015/11/13 06:00
MHDA- 2016/08/11 06:00
CRDT- 2015/11/13 06:00
PHST- 2015/11/13 06:00 [entrez]
PHST- 2015/11/13 06:00 [pubmed]
PHST- 2016/08/11 06:00 [medline]
AID - 05ab5a7e40e7ba9a,7c299d056429d3d1 [pii]
AID - 10.1615/intjmedmushrooms.v17.i7.70 [doi]
PST - ppublish
SO  - Int J Med Mushrooms. 2015;17(7):671-80. doi: 10.1615/intjmedmushrooms.v17.i7.70.