PMID- 26560726 OWN - NLM STAT- MEDLINE DCOM- 20170227 LR - 20200330 IS - 1432-1084 (Electronic) IS - 0938-7994 (Linking) VI - 26 IP - 8 DP - 2016 Aug TI - Third-generation dual-source CT of the neck using automated tube voltage adaptation in combination with advanced modeled iterative reconstruction: evaluation of image quality and radiation dose. PG - 2623-31 LID - 10.1007/s00330-015-4099-z [doi] AB - PURPOSE: To evaluate image quality and radiation dose in third-generation dual-source computed tomography (DSCT) of the neck using automated tube voltage adaptation (TVA) with advanced modelled iterative reconstruction (ADMIRE) algorithm. METHODS: One hundred and sixteen patients were retrospectively evaluated. Group A (n = 59) was examined on second-generation DSCT with automated TVA and filtered back projection. Group B (n = 57) was examined on a third-generation DSCT with automated TVA and ADMIRE. Age, body diameter, attenuation of several anatomic structures, noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), radiation dose (CTDIvol) and size-specific dose estimates (SSDE) were assessed. Diagnostic acceptability was rated by three readers. RESULTS: Age (p = 0.87) and body diameter (p = 0.075) did not differ significantly. Tube voltage in Group A was set automatically to 100 kV for all patients (n = 59), and to 70 kV (n = 2), 80 kV (n = 5), and 90 kV (n = 50) in Group B. Noise was reduced and CNR was increased significantly (p < 0.001). Diagnostic acceptability was rated high in both groups, with better ratings in Group B (p < 0.001). SSDE was reduced by 34 % in Group B (20.38 +/- 1.63 mGy vs. 13.04 +/- 1.50 mGy, p < 0.001). CONCLUSION: Combination of automated TVA and ADMIRE in neck CT using third-generation DSCT results in a substantial radiation dose reduction with low noise and increased CNR. KEY POINTS: * Third-generation DSCT provides automated tube voltage adaptation with an increment of 10 kV. * 10 kV increment optimizes scans to the patient's neck anatomy. * TVA combined with ADMIRE significantly lower radiation dose in contrast-enhanced neck CT. * TVA in combination with ADMIRE reduces noise and increases SNR and CNR. * Image analysis quoted less noise and better diagnostic acceptability in third-generation DSCT. FAU - Scholtz, Jan-Erik AU - Scholtz JE AUID- ORCID: 0000-0003-4631-6126 AD - Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. janerikscholtz@gmail.com. FAU - Wichmann, Julian L AU - Wichmann JL AD - Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. AD - Institut fur Diagnostische und Interventionelle Radiologie, Universitatsklinikum Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. FAU - Husers, Kristina AU - Husers K AD - Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. AD - Institut fur Diagnostische und Interventionelle Radiologie, Universitatsklinikum Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. FAU - Albrecht, Moritz H AU - Albrecht MH AD - Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. AD - Institut fur Diagnostische und Interventionelle Radiologie, Universitatsklinikum Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. FAU - Beeres, Martin AU - Beeres M AD - Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. AD - Institut fur Diagnostische und Interventionelle Radiologie, Universitatsklinikum Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. FAU - Bauer, Ralf W AU - Bauer RW AD - Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. AD - Institut fur Diagnostische und Interventionelle Radiologie, Universitatsklinikum Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. FAU - Vogl, Thomas J AU - Vogl TJ AD - Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. AD - Institut fur Diagnostische und Interventionelle Radiologie, Universitatsklinikum Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. FAU - Bodelle, Boris AU - Bodelle B AD - Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. AD - Institut fur Diagnostische und Interventionelle Radiologie, Universitatsklinikum Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany. LA - eng PT - Journal Article DEP - 20151111 PL - Germany TA - Eur Radiol JT - European radiology JID - 9114774 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - *Algorithms MH - Female MH - Humans MH - Image Processing, Computer-Assisted MH - Male MH - Middle Aged MH - Neck/*diagnostic imaging MH - Radiation Dosage MH - Radiographic Image Interpretation, Computer-Assisted/*methods MH - Retrospective Studies MH - Signal-To-Noise Ratio MH - Tomography, X-Ray Computed/*methods MH - Young Adult OTO - NOTNLM OT - ADMIRE OT - Automated tube voltage adaptation OT - Iterative reconstruction OT - Neck OT - Third-generation dual-source CT EDAT- 2015/11/13 06:00 MHDA- 2017/02/28 06:00 CRDT- 2015/11/13 06:00 PHST- 2015/03/13 00:00 [received] PHST- 2015/10/29 00:00 [accepted] PHST- 2015/10/28 00:00 [revised] PHST- 2015/11/13 06:00 [entrez] PHST- 2015/11/13 06:00 [pubmed] PHST- 2017/02/28 06:00 [medline] AID - 10.1007/s00330-015-4099-z [pii] AID - 10.1007/s00330-015-4099-z [doi] PST - ppublish SO - Eur Radiol. 2016 Aug;26(8):2623-31. doi: 10.1007/s00330-015-4099-z. Epub 2015 Nov 11.