PMID- 26562483
OWN - NLM
STAT- MEDLINE
DCOM- 20161031
LR  - 20161230
IS  - 1365-2265 (Electronic)
IS  - 0300-0664 (Linking)
VI  - 84
IP  - 1
DP  - 2016 Jan
TI  - When and how should patients with multiple endocrine neoplasia type 1 be screened 
      for thymic and bronchial carcinoid tumours?
PG  - 13-6
LID - 10.1111/cen.12972 [doi]
AB  - Patients with multiple endocrine neoplasia type 1 (MEN1) are commonly evaluated 
      for clinical manifestations of this syndrome with the rationale that early 
      diagnosis and adequate treatment will result in improved survival and quality of 
      life. Thymic and bronchial carcinoid tumours are uncommon but important 
      manifestations of MEN1. Current practice guidelines recommend evaluation with 
      computed tomography or magnetic resonance imaging scan of the chest every 1-2 
      years to detect these neoplasms. However, the certainty that patients will be 
      better off (increased survival or quality of life) as a result of this case 
      detection strategy is based on evidence at moderate-high risk of bias that yields 
      only imprecise results of indirect relevance to these patients. In order to 
      improve the care that patients with MEN1 receive, co-ordinated efforts from 
      different stakeholders are required so that large, prospective, multicentre 
      studies evaluating patient important outcomes are carried out.
CI  - (c) 2015 John Wiley & Sons Ltd.
FAU - Singh Ospina, Naykky
AU  - Singh Ospina N
AD  - Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of 
      Medicine, Mayo Clinic, Rochester, MN, USA.
AD  - Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, 
      Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, MN, 
      USA.
FAU - Maraka, Spyridoula
AU  - Maraka S
AD  - Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of 
      Medicine, Mayo Clinic, Rochester, MN, USA.
AD  - Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, 
      Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, MN, 
      USA.
FAU - Montori, Victor
AU  - Montori V
AD  - Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of 
      Medicine, Mayo Clinic, Rochester, MN, USA.
AD  - Knowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, 
      Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, MN, 
      USA.
FAU - Thompson, Geoffrey B
AU  - Thompson GB
AD  - Department of Surgery, Mayo Clinic, Rochester, MN, USA.
FAU - Young, William F Jr
AU  - Young WF Jr
AD  - Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of 
      Medicine, Mayo Clinic, Rochester, MN, USA.
LA  - eng
PT  - Journal Article
DEP - 20151210
PL  - England
TA  - Clin Endocrinol (Oxf)
JT  - Clinical endocrinology
JID - 0346653
SB  - IM
MH  - Bronchial Neoplasms/complications/*diagnosis
MH  - Carcinoid Tumor/complications/*diagnosis
MH  - Early Detection of Cancer/*methods
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Multiple Endocrine Neoplasia Type 1/complications/*diagnosis
MH  - Quality of Life
MH  - Risk Factors
MH  - Thymus Neoplasms/complications/*diagnosis
MH  - Time Factors
MH  - Tomography, X-Ray Computed
EDAT- 2015/11/13 06:00
MHDA- 2016/11/01 06:00
CRDT- 2015/11/13 06:00
PHST- 2015/09/28 00:00 [received]
PHST- 2015/10/22 00:00 [revised]
PHST- 2015/11/03 00:00 [revised]
PHST- 2015/11/05 00:00 [accepted]
PHST- 2015/11/13 06:00 [entrez]
PHST- 2015/11/13 06:00 [pubmed]
PHST- 2016/11/01 06:00 [medline]
AID - 10.1111/cen.12972 [doi]
PST - ppublish
SO  - Clin Endocrinol (Oxf). 2016 Jan;84(1):13-6. doi: 10.1111/cen.12972. Epub 2015 Dec 
      10.