PMID- 2656839
OWN - NLM
STAT- MEDLINE
DCOM- 19890710
LR  - 20061115
IS  - 0368-2315 (Print)
IS  - 0150-9918 (Linking)
VI  - 18
IP  - 2
DP  - 1989
TI  - [Fertilization in vitro and embryo transfer (FIVET) and endometriosis. 
      Uncertainties and issues].
PG  - 241-8
AB  - The progressive improvements in the results and extra simplification of the 
      recent techniques for in vitro fertilisation and embryo transfer (IVFET) have 
      contributed to broadening the indications for this method of assisted 
      reproduction. Endometriosis has not escaped this evolution and more and more 
      works referring to the use of IVFET for this indication. All the same, there are 
      many questions which have not been clearly answered. The possible variety of 
      causes for this condition, the number of factors that may be causing the 
      infertility, make it difficult to assess completely the method of therapy, and 
      require that controlled studies should carried out. These are not always easy to 
      perform. IVFET is no exception to these difficulties. The relationships between 
      endometriosis and infertility are complex and very often difficult to assess. All 
      the same, very many hypotheses have been put out to explain the deleterious 
      effect of this abnormality. Certain mechanisms have been suggested (such as 
      troubles with maturation of the follicle and of the oocyte and the production of 
      a hostile environment for the gametes and for the embryo). These are logical 
      arguments for IVFET which initially produces follicular maturation and takes the 
      gametes and the embryo away from the peritoneal and tubal environment. In spite 
      of certain hypotheses which would be unfavourable in cases of endometriosis 
      (oocytes being less likely to be fertilised, poorer quality of the embryos, 
      defective implantation...) the results that have been obtained after IVFET are 
      overall very favourable and certainly can compare with those obtained when it has 
      been used for, for instance, tubal indication.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Audebert, A J
AU  - Audebert AJ
AD  - Institute Robert B. Greenblatt, Bordeaux.
FAU - Joyau-Perraguin, S
AU  - Joyau-Perraguin S
FAU - Emperaire, J C
AU  - Emperaire JC
LA  - fre
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - FIVETE et endometriose. Incertitudes et enjeux.
PL  - France
TA  - J Gynecol Obstet Biol Reprod (Paris)
JT  - Journal de gynecologie, obstetrique et biologie de la reproduction
JID - 0322206
SB  - IM
MH  - *Embryo Transfer
MH  - Endometriosis/*complications
MH  - Female
MH  - *Fertilization in Vitro
MH  - Humans
MH  - Infertility, Female/etiology
RF  - 53
EDAT- 1989/01/01 00:00
MHDA- 1989/01/01 00:01
CRDT- 1989/01/01 00:00
PHST- 1989/01/01 00:00 [pubmed]
PHST- 1989/01/01 00:01 [medline]
PHST- 1989/01/01 00:00 [entrez]
PST - ppublish
SO  - J Gynecol Obstet Biol Reprod (Paris). 1989;18(2):241-8.