PMID- 26572395
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160304
LR  - 20151117
IS  - 1879-1344 (Electronic)
IS  - 0144-8617 (Linking)
VI  - 136
DP  - 2016 Jan 20
TI  - Tragacanth gum-based nanogel as a superparamagnetic molecularly imprinted polymer 
      for quercetin recognition and controlled release.
PG  - 630-40
LID - S0144-8617(15)00853-X [pii]
LID - 10.1016/j.carbpol.2015.09.006 [doi]
AB  - A highly selective magnetic molecularly imprinted polymer (MMIP) with core-shell 
      structure has been synthesized by a sol-gel process composed of Tragacanth Gum 
      (TG) crosslinker, Fe3O4/SiO2 nanoparticles, and N-vinyl imidazole(VI) functional 
      monomer in the presence of template Quercetin (QC). Different techniques 
      including scanning electron microscopy (SEM), SEM-energy dispersive spectroscopy 
      (SEM-EDS), vibrating sample magnetometer (VSM), and transmission electron 
      microscopy (TEM) were used to verify the successful synthesis of MIP on the 
      surface of Fe3O4/SiO2 nanoparticles. The swelling behavior of MMIP, its 
      recognition and selectivity for QC and structural analog, Catechin (CT), were 
      tested and compared with magnetic non imprinted polymer (MNIP). MMIP adsorbs the 
      template drug quickly and equilibrium could be reached in 2h. The mechanism for 
      adsorption was found to follow the Langmuir model with the maximum capacity of 
      175.43 mg g(-1). The MMIP indicated excellent recognition and binding affinity 
      toward QC, selectivity factor (varepsilon) relative to CT was 2.16. Finally, the MMIP was 
      evaluated as a drug delivery device by performing in vitro release studies in 
      PBS.
CI  - Copyright (c) 2015 Elsevier Ltd. All rights reserved.
FAU - Hemmati, Khadijeh
AU  - Hemmati K
AD  - Polymer Research Laboratory, Faculty of Chemistry, University of Mazandaran, 
      Babolsar, Iran.
FAU - Masoumi, Arameh
AU  - Masoumi A
AD  - Polymer Research Laboratory, Faculty of Chemistry, University of Mazandaran, 
      Babolsar, Iran.
FAU - Ghaemy, Mousa
AU  - Ghaemy M
AD  - Polymer Research Laboratory, Faculty of Chemistry, University of Mazandaran, 
      Babolsar, Iran. Electronic address: ghaemy@umz.ac.ir.
LA  - eng
PT  - Journal Article
DEP - 20150904
PL  - England
TA  - Carbohydr Polym
JT  - Carbohydrate polymers
JID - 8307156
OTO - NOTNLM
OT  - Drug delivery
OT  - Magnetic molecularly imprinted polymer
OT  - Quercetin
OT  - Recognition and selective adsorption
OT  - Tragacanth gum
OT  - Vinyl imidazole
EDAT- 2015/11/18 06:00
MHDA- 2015/11/18 06:01
CRDT- 2015/11/18 06:00
PHST- 2015/03/24 00:00 [received]
PHST- 2015/08/28 00:00 [revised]
PHST- 2015/09/01 00:00 [accepted]
PHST- 2015/11/18 06:00 [entrez]
PHST- 2015/11/18 06:00 [pubmed]
PHST- 2015/11/18 06:01 [medline]
AID - S0144-8617(15)00853-X [pii]
AID - 10.1016/j.carbpol.2015.09.006 [doi]
PST - ppublish
SO  - Carbohydr Polym. 2016 Jan 20;136:630-40. doi: 10.1016/j.carbpol.2015.09.006. Epub 
      2015 Sep 4.