PMID- 26576946 OWN - NLM STAT- MEDLINE DCOM- 20160531 LR - 20220321 IS - 1747-597X (Electronic) IS - 1747-597X (Linking) VI - 10 DP - 2015 Nov 14 TI - The efficacy of a blended motivational interviewing and problem solving therapy intervention to reduce substance use among patients presenting for emergency services in South Africa: A randomized controlled trial. PG - 46 LID - 10.1186/s13011-015-0042-1 [doi] LID - 46 AB - BACKGROUND: The treatment of substance use disorders is a public health priority, particularly in South Africa where the prevalence of these disorders is high. We tested two peer-counsellor delivered brief interventions (BIs) for risky substance use among adults presenting to emergency departments (EDs) in South Africa. METHODS: In this randomised controlled trial, we enrolled patients presenting to one of three 24-hour EDs who screened at risk for substance use according to the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST). Eligible patients were randomly allocated to one of three conditions: Motivational Interviewing (MI), blended MI and Problem Solving Therapy (MI-PST) or a Psycho-educational Control Group (CG). The primary outcome was reduction in ASSIST scores at three months follow-up. RESULTS: Of the 2736 patients screened, 335 met inclusion criteria, were willing to participate in the intervention and were randomised to one of three conditions: 113 to MI, 112 to MI-PST and 110 to CG. ASSIST scores at three months were lower in the MI-PST group than they were in the MI and CG groups (adjusted mean difference of -1.72, 95 % CI -3.36 - -0.08). We recorded no significant difference in ASSIST scores between the CG and MI group (adjusted mean difference of -0.02, 95 % CI -2.01 - 1.96). CONCLUSION: With the addition of minimal resources, BIs are feasible to conduct in EDs in a low resourced country. These preliminary findings report that MI-PST appears to be an effective BI for reducing substance use among at risk participants. Further research is required to replicate these findings with effort to limit attrition, to determine whether reductions in substance use are persistent at 6 and 12 month follow-up and whether parallel changes occur in other indications of treatment outcomes, such as injury rates and ED presentations. TRIAL REGISTRATION: This trial registered with the Pan African Clinical Trial Registry (PACTR201308000591418). FAU - Sorsdahl, K AU - Sorsdahl K AD - Alan J. Flisher Centre for Public Mental Health, Department of Psychiatry & Mental Health, University of Cape Town, Groote Schuur Hospital, Cape Town, 7925, South Africa. Katherine.sorsdahl@uct.ac.za. FAU - Stein, D J AU - Stein DJ AD - Department of Psychiatry & Mental Health, University of Cape Town, Groote Schuur Hospital, Cape Town, 7925, South Africa. dan.stein@uct.ac.za. FAU - Corrigall, J AU - Corrigall J AD - Western Cape Department of Health, 8 Riebeeck Street, Cape Town, 8001, South Africa. joannecor@gmail.com. FAU - Cuijpers, P AU - Cuijpers P AD - Department of Clinical Psychology, Faculty of Psychology and Education, VU University Amsterdam, Amsterdam, The Netherlands. p.cuijpers@vu.nl. FAU - Smits, N AU - Smits N AD - Department of Clinical Psychology, Faculty of Psychology and Education, VU University Amsterdam, Amsterdam, The Netherlands. n.smits@vu.nl. FAU - Naledi, T AU - Naledi T AD - Western Cape Department of Health, 8 Riebeeck Street, Cape Town, 8001, South Africa. Tracey.Naledi@westerncape.gov.za. FAU - Myers, B AU - Myers B AD - Department of Psychiatry & Mental Health, University of Cape Town, Groote Schuur Hospital, Cape Town, 7925, South Africa. bronwyn.myers@mrc.ac.za. AD - Alcohol, Tobacco, and Other Drug Research Unit, South African Medical Research Council, PO Box 19070, Tygerberg, 7505, South Africa. bronwyn.myers@mrc.ac.za. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20151114 PL - England TA - Subst Abuse Treat Prev Policy JT - Substance abuse treatment, prevention, and policy JID - 101258060 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Emergency Medical Services/*methods MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Motivational Interviewing MH - *Problem Solving MH - Psychotherapy, Brief MH - South Africa MH - Substance-Related Disorders/*therapy MH - Treatment Outcome MH - Young Adult PMC - PMC4650345 EDAT- 2015/11/19 06:00 MHDA- 2016/06/01 06:00 PMCR- 2015/11/14 CRDT- 2015/11/19 06:00 PHST- 2015/06/10 00:00 [received] PHST- 2015/11/08 00:00 [accepted] PHST- 2015/11/19 06:00 [entrez] PHST- 2015/11/19 06:00 [pubmed] PHST- 2016/06/01 06:00 [medline] PHST- 2015/11/14 00:00 [pmc-release] AID - 10.1186/s13011-015-0042-1 [pii] AID - 42 [pii] AID - 10.1186/s13011-015-0042-1 [doi] PST - epublish SO - Subst Abuse Treat Prev Policy. 2015 Nov 14;10:46. doi: 10.1186/s13011-015-0042-1.