PMID- 26592570
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160615
LR  - 20151123
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 147
DP  - 2016 Jan 15
TI  - Development and validation of a method for the quantification of extractable 
      perfluoroalkyl acids (PFAAs) and perfluorooctane sulfonamide (FOSA) in textiles.
PG  - 8-15
LID - S0039-9140(15)30314-3 [pii]
LID - 10.1016/j.talanta.2015.09.021 [doi]
AB  - In textiles, like outdoor clothing, per- and polyfluoroalkyl substances (PFASs) 
      are often used for durable water repellency (DWR) of the final products. The 
      analytical performance to determine the concentration of these chemicals 
      available for exposure to humans and to the environment need to be established. 
      Here a method for the extraction and analysis of one class of PFASs, namely 
      perfluoroalkyl acids (PFAAs), in outdoor clothing was developed and validated. 
      The PFAAs which were validated, included perfluoroalkyl carboxylic acids (PFCAs) 
      (C4-C14), and perfluoroalkane sulfonic acids (PFSAs) (C4, C6, C7, C8). In 
      addition, perfluorooctane sulfonamide (FOSA) was included in this study. The 
      method was based on an organic solvent extraction and analysis by 
      high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). No 
      further cleaning was needed. Two commonly used organic solvent compositions were 
      evaluated for the optimal extraction, i.e. methanol and acetone/acetonitrile 
      (80:20, v/v), and the number and duration of the sequential extractions were 
      optimized. Results showed that two sequential extractions with 5mL methanol and 
      an extraction time of 30min gave an optimal performance with an extraction 
      efficiency of >90%. The influence of matrix on the quantification of PFAAs was 
      studied. This indicated ion suppression due to different matrix effects or 
      sorption behavior to specific textile samples. Validation of the entire method 
      showed overall recoveries of>80% and relative standard deviations (RSDs) of<9% 
      (n=3) for repeatability and <20% (n=3) for reproducibility. This is the first 
      validation of an analytical method for the analysis of extractable PFCAs, PFSAs 
      and FOSA associated to textiles, which is of high importance due to the 
      regulation of PFAAs in textile.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - van der Veen, Ike
AU  - van der Veen I
AD  - VU University, Institute for Environmental Studies (IVM), De Boelelaan 1087, 1081 
      HV Amsterdam, The Netherlands. Electronic address: ike.vander.veen@vu.nl.
FAU - Weiss, Jana M
AU  - Weiss JM
AD  - VU University, Institute for Environmental Studies (IVM), De Boelelaan 1087, 1081 
      HV Amsterdam, The Netherlands.
FAU - Hanning, Anne-Charlotte
AU  - Hanning AC
AD  - Swerea IVF, Argongatan 30, SE-431 53 Molndal, Sweden.
FAU - de Boer, Jacob
AU  - de Boer J
AD  - VU University, Institute for Environmental Studies (IVM), De Boelelaan 1087, 1081 
      HV Amsterdam, The Netherlands.
FAU - Leonards, Pim E G
AU  - Leonards PE
AD  - VU University, Institute for Environmental Studies (IVM), De Boelelaan 1087, 1081 
      HV Amsterdam, The Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20150914
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
OTO - NOTNLM
OT  - Method development
OT  - Perfluoroalkane sulfonic acids
OT  - Perfluoroalkyl acids
OT  - Perfluoroalkyl carboxylic acids
OT  - Perfluorooctane sulfonamide
OT  - Textile
EDAT- 2015/11/26 06:00
MHDA- 2015/11/26 06:01
CRDT- 2015/11/24 06:00
PHST- 2015/07/06 00:00 [received]
PHST- 2015/09/07 00:00 [revised]
PHST- 2015/09/08 00:00 [accepted]
PHST- 2015/11/24 06:00 [entrez]
PHST- 2015/11/26 06:00 [pubmed]
PHST- 2015/11/26 06:01 [medline]
AID - S0039-9140(15)30314-3 [pii]
AID - 10.1016/j.talanta.2015.09.021 [doi]
PST - ppublish
SO  - Talanta. 2016 Jan 15;147:8-15. doi: 10.1016/j.talanta.2015.09.021. Epub 2015 Sep 
      14.