PMID- 26592690
OWN - NLM
STAT- MEDLINE
DCOM- 20160811
LR  - 20181202
IS  - 1096-0260 (Electronic)
IS  - 0091-7435 (Linking)
VI  - 82
DP  - 2016 Jan
TI  - Prostate cancer screening practices and diagnoses in patients age 50 and older, 
      Southeastern Michigan, pre/post 2012.
PG  - 73-6
LID - S0091-7435(15)00344-8 [pii]
LID - 10.1016/j.ypmed.2015.11.017 [doi]
AB  - INTRODUCTION: Studies investigating the regional impact of the 2012 U.S. 
      Preventive Services Task Force (USPSTF) recommendation against the use of 
      prostate specific antigen (PSA) screening for prostate cancer have been limited. 
      METHODS: A retrospective cohort study was conducted on men age 50years and older 
      in Southeastern Michigan pre (n=3647) and post (n=3618) USPSTF recommendation. 
      PSA screening, transrectal ultrasound, and prostate biopsy rates were evaluated 
      pre/post using a generalized piecewise linear model with a Poisson distribution, 
      and log link. A knot was placed at year 2011 to estimate pre/post slope 
      coefficients. Generalized estimating equations were used to estimate the marginal 
      probability of a prostate diagnosis as a logistic function of pre and 
      post-period, and comorbidities. RESULTS: PSA utilization significantly increased 
      (beta=0.28; 95% CI: 0.25, 0.31) during the pre-period, but significantly decreased 
      in the post-period (beta=-0.29; 95% CI: -0.34, -0.25). Prostate biopsies decreased 
      pre (beta=-0.16; 95% CI: -0.25, -0.08) and did not change post (beta=0.01; 95% CI: 
      -0.09, 0.12). Transrectal ultrasounds were stable pre (beta=0.16; 95% CI: -0.03, 
      0.35) and significantly decreased post (beta=-0.27; 95% CI: -0.50, -0.04). Patients 
      in the post-period had a decreased probability of having a diagnosis of prostate 
      cancer (OR: 0.81; 95% CI: 0.74-0.89) compared to the pre-period. CONCLUSION: Our 
      study demonstrates how PSA tests are still being frequently used in Southeastern 
      Michigan. Further research is needed to better understand regional variation in 
      prostate cancer screening practices in the U.S.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Rezaee, Michael E
AU  - Rezaee ME
AD  - Oakland University William Beaumont School of Medicine, Rochester, MI, United 
      States. Electronic address: merezaee@oakland.edu.
FAU - Ward, Charlotte E
AU  - Ward CE
AD  - Center for Healthcare Studies, Feinberg School of Medicine, Northwestern 
      University, Chicago, IL, United States.
FAU - Odom, Brian D
AU  - Odom BD
AD  - Oakland University William Beaumont School of Medicine, Rochester, MI, United 
      States.
FAU - Pollock, Martha
AU  - Pollock M
AD  - Oakland University William Beaumont School of Medicine, Rochester, MI, United 
      States.
LA  - eng
GR  - T32 HS000084/HS/AHRQ HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20151122
PL  - United States
TA  - Prev Med
JT  - Preventive medicine
JID - 0322116
RN  - EC 3.4.21.77 (Prostate-Specific Antigen)
SB  - IM
MH  - Advisory Committees
MH  - Aged
MH  - Early Detection of Cancer/*statistics & numerical data
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Mass Screening/*statistics & numerical data
MH  - Michigan
MH  - Middle Aged
MH  - Prostate-Specific Antigen/*blood
MH  - Prostatic Neoplasms/blood/*diagnosis
MH  - Retrospective Studies
MH  - United States
OTO - NOTNLM
OT  - Healthcare utilization
OT  - Population health
OT  - Prostate cancer screening
OT  - Prostate specific antigen
EDAT- 2015/11/26 06:00
MHDA- 2016/08/12 06:00
CRDT- 2015/11/24 06:00
PHST- 2015/07/20 00:00 [received]
PHST- 2015/11/10 00:00 [revised]
PHST- 2015/11/15 00:00 [accepted]
PHST- 2015/11/24 06:00 [entrez]
PHST- 2015/11/26 06:00 [pubmed]
PHST- 2016/08/12 06:00 [medline]
AID - S0091-7435(15)00344-8 [pii]
AID - 10.1016/j.ypmed.2015.11.017 [doi]
PST - ppublish
SO  - Prev Med. 2016 Jan;82:73-6. doi: 10.1016/j.ypmed.2015.11.017. Epub 2015 Nov 22.