PMID- 26613224
OWN - NLM
STAT- MEDLINE
DCOM- 20160623
LR  - 20181202
IS  - 2791-6421 (Electronic)
IS  - 0041-4301 (Linking)
VI  - 57
IP  - 1
DP  - 2015 Jan-Feb
TI  - Human herpesvirus 6 infection mimicking measles: two pediatric cases.
PG  - 74-7
AB  - Measles is a highly contagious viral infection associated with clinical symptoms 
      such as fever, cough, conjunctivitis, coryza, eruption and increased serum 
      immunoglobulin M (IgM) antibodies. A clinical diagnosis is easily established 
      when the chain of infection can be followed. However, Japan is currently 
      experiencing sporadic measles outbreaks, which complicate the establishment of 
      diagnosis. Furthermore, other exanthematous infections such as rubella, human 
      parvovirus B19, human herpesvirus 6 (HHV-6) and HHV-7 present with clinical 
      symptoms and IgM antibody levels similar to those in measles. Therefore, 
      real-time polymerase chain reaction virogene testing has been part of Japan's 
      standard diagnostic protocol for measles since 2010. This report presents two 
      pediatric cases clinically resembling measles that were diagnosed as HHV-6 based 
      on a virogene detection test. This underscores the importance of performing 
      pathogen testing to confirm a diagnosis when measles is suspected.
FAU - Goto, Masahide
AU  - Goto M
AD  - Department of Pediatrics, Hitachiomiya Saiseikai Hospital, Ibaraki Prefectural 
      Institute of Public Health, Ibaraki, Japan. masapon.go@gmail.com.
FAU - Kumagai, Hideki
AU  - Kumagai H
FAU - Kawamata, Ryou
AU  - Kawamata R
FAU - Matsumoto, Shizuko
AU  - Matsumoto S
FAU - Watanabe, Miki
AU  - Watanabe M
FAU - Nozaki, Yasuyuki
AU  - Nozaki Y
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Turkey
TA  - Turk J Pediatr
JT  - The Turkish journal of pediatrics
JID - 0417505
RN  - 0 (Antibodies, Viral)
RN  - 0 (Immunoglobulin M)
SB  - IM
MH  - Antibodies, Viral/analysis
MH  - Child, Preschool
MH  - Diagnosis, Differential
MH  - Herpesvirus 6, Human/*isolation & purification
MH  - Humans
MH  - Immunoglobulin M/blood
MH  - Japan
MH  - Male
MH  - Measles/*diagnosis
MH  - Real-Time Polymerase Chain Reaction
MH  - Roseolovirus Infections/*diagnosis
EDAT- 2015/11/28 06:00
MHDA- 2016/06/24 06:00
CRDT- 2015/11/28 06:00
PHST- 2015/11/28 06:00 [entrez]
PHST- 2015/11/28 06:00 [pubmed]
PHST- 2016/06/24 06:00 [medline]
PST - ppublish
SO  - Turk J Pediatr. 2015 Jan-Feb;57(1):74-7.