PMID- 26613523
OWN - NLM
STAT- MEDLINE
DCOM- 20170104
LR  - 20181113
IS  - 1423-0151 (Electronic)
IS  - 1011-7571 (Print)
IS  - 1011-7571 (Linking)
VI  - 25
IP  - 2
DP  - 2016
TI  - Echocardiographic Evaluation of Biventricular Function in Patients with Euthyroid 
      Hashimoto's Thyroiditis.
PG  - 143-9
LID - 10.1159/000442709 [doi]
AB  - OBJECTIVE: The aim of this study was to evaluate the left (LV) and right (RV) 
      ventricular function in euthyroid Hashimoto's thyroiditis (eHT) patients. 
      SUBJECTS AND METHODS: Forty-five patients diagnosed with eHT and 45 age- and 
      gender-matched control subjects were enrolled in this study. Echocardiographic 
      parameters reflecting RV and LV functions such as chamber dimensions, ejection 
      fraction, fractional shortening, conventional and tissue Doppler-derived early 
      and late filling velocities (E, A, E', A'), isovolumic relaxation (IVRT) and 
      contraction (IVCT) times, ejection time (ET), deceleration time (DT), Tei index, 
      pulmonary acceleration time (PAcT) and tricuspid annular plane systolic excursion 
      (TAPSE) of patients with eHT were compared to those of control subjects using the 
      paired-samples t test or Wilcoxon signed-rank test. RESULTS: Regarding the LV 
      function, compared to the controls patients with eHT had a higher LV-Tei index 
      (0.6 +/- 0.2 vs. 0.4 +/- 0.1, p < 0.001), higher DT (p < 0.001) and IVRT (p < 0.001) 
      values, and higher E/E' ratios (p = 0.04). In contrast, the peak E wave velocity 
      (p = 0.02), E/A ratio (p = 0.01) and ET (p = 0.02) were significantly lower in 
      the eHT group than amongst the controls. The RV, Tei index (0.40 +/- 0.11 vs. 0.28 
      +/- 0.07, p < 0.001), TAPSE (2.0 +/- 0.3 vs. 2.2 +/- 0.2 mm, p < 0.001), PAcT (124.3 +/- 
      22.6 vs. 149.4 +/- 18.3 ms, p < 0.001), A' (p = 0.007) and IVCT (p = 0.001) were 
      significantly higher in patients with eHT than the controls. However, the 
      tricuspid E/A ratio (p = 0.01), E' (p = 0.03) and E'/A' ratio (p = 0.001) were 
      significantly lower in the eHT patients than the control group. CONCLUSIONS: This 
      study demonstrated that both RV and LV functions were impaired in patients with 
      eHT.
CI  - (c) 2015 S. Karger AG, Basel.
FAU - Vatan, Mehmet Bulent
AU  - Vatan MB
AD  - Department of Cardiology, Sakarya University Training and Research Hospital, 
      Sakarya, Turkey.
FAU - Varim, Ceyhun
AU  - Varim C
FAU - Agac, Mustafa Tarik
AU  - Agac MT
FAU - Varim, Perihan
AU  - Varim P
FAU - Cakar, Mehmet Akif
AU  - Cakar MA
FAU - Aksoy, Murat
AU  - Aksoy M
FAU - Erkan, Hakan
AU  - Erkan H
FAU - Yilmaz, Sabiye
AU  - Yilmaz S
FAU - Kilic, Harun
AU  - Kilic H
FAU - Gunduz, Huseyin
AU  - Gunduz H
FAU - Akdemir, Ramazan
AU  - Akdemir R
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20151125
PL  - Switzerland
TA  - Med Princ Pract
JT  - Medical principles and practice : international journal of the Kuwait University, 
      Health Science Centre
JID - 8901334
SB  - IM
MH  - Echocardiography, Doppler/*methods
MH  - Female
MH  - Hashimoto Disease/*diagnostic imaging/pathology
MH  - Heart Ventricles/*diagnostic imaging/pathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Tricuspid Valve/*diagnostic imaging/pathology
MH  - Ventricular Dysfunction/*diagnostic imaging
MH  - Ventricular Function, Left
PMC - PMC5588360
EDAT- 2015/11/28 06:00
MHDA- 2017/01/05 06:00
PMCR- 2015/11/25
CRDT- 2015/11/28 06:00
PHST- 2015/03/31 00:00 [received]
PHST- 2015/11/24 00:00 [accepted]
PHST- 2015/11/28 06:00 [entrez]
PHST- 2015/11/28 06:00 [pubmed]
PHST- 2017/01/05 06:00 [medline]
PHST- 2015/11/25 00:00 [pmc-release]
AID - 000442709 [pii]
AID - mpp-0025-0143 [pii]
AID - 10.1159/000442709 [doi]
PST - ppublish
SO  - Med Princ Pract. 2016;25(2):143-9. doi: 10.1159/000442709. Epub 2015 Nov 25.