PMID- 26613929 OWN - NLM STAT- MEDLINE DCOM- 20160614 LR - 20181202 IS - 1749-8090 (Electronic) IS - 1749-8090 (Linking) VI - 10 DP - 2015 Nov 27 TI - Long-term outcomes of pericardiectomy for constrictive pericarditis. PG - 177 LID - 10.1186/s13019-015-0385-8 [doi] LID - 177 AB - BACKGROUND: Constrictive pericarditis is a rare and disabling disease that can result in chronic fibrous thickening of the pericardium. The purpose of this study was to evaluate the long-term outcomes following treatment of constrictive pericarditis by pericardiectomy. METHODS: Between September 1992 and May 2014, 47 patients who underwent pericardiectomy for constrictive pericarditis were retrospectively examined. Demographic, pre-, intra- and postoperative data and long-term outcomes were analyzed. RESULTS: Thirty of the patients were male, the mean age was 45.8 +/- 16.7. Aetiology of constrictive pericarditis was tuberculosis in 22 (46.8 %) patients, idiopathic in 15 (31.9 %), malignancy in 3 (6.4 %), prior cardiac surgery in 2 (4.3 %), non-tuberculosis bacterial infections in 2 (4.3 %), radiotherapy in 1 (2.1 %), uraemia in 1 (2.1 %) and post-traumatic in 1 (2.1 %). The surgical approach was achieved via a median sternotomy in all patients except only 1 patient. The mean operative time was 156.4 +/- 45.7 min. Improvement in functional status in 80 % of patients' at least one New York Heart Association (NYHA) functional class was observed. In-hospital mortality rate was 2.1 % (1 of 47 patients). The cause of death was pneumonia leading to progressive respiratory failure. The late mortality rate was 23.4 % (11 of 47 patients). The mean follow-up time was 61.2 +/- 66 months. The actuarial survival rates were 91 %, 85 % and 81 % at 1, 5 and 10 years, respectively. Recurrence requiring a repeat pericardiectomy was developed in no patient during follow-up. CONCLUSION: Pericardiectomy is associated with high morbidity and mortality rates. Cases with neoplastic diseases, diminished cardiac output, cases in need of reoperation are expected to have high mortality rates and less chance of functional recovery. FAU - Bicer, Murat AU - Bicer M AD - Department of Cardiovascular Surgery, Uludag University Medical Faculty, Bursa, Turkey. mbicer23@yahoo.com. FAU - Ozdemir, Bulent AU - Ozdemir B AD - Department of Cardiology, Uludag University Medical Faculty, Gorukle Kampusu, Nilufer, Bursa, 16000, Turkey. buloz2@yahoo.com. FAU - Kan, Iris AU - Kan I AD - Department of Cardiovascular Surgery, Uludag University Medical Faculty, Bursa, Turkey. iriskan64@hotmail.com. FAU - Yuksel, Ahmet AU - Yuksel A AD - Department of Cardiovascular Surgery, Uludag University Medical Faculty, Bursa, Turkey. ahmetyuksel1982@mynet.com. FAU - Tok, Mustafa AU - Tok M AD - Department of Cardiovascular Surgery, Uludag University Medical Faculty, Bursa, Turkey. mustafatok@uludag.edu.tr. FAU - Senkaya, Isik AU - Senkaya I AD - Department of Cardiovascular Surgery, Uludag University Medical Faculty, Bursa, Turkey. senkaya@uludag.edu.tr. LA - eng PT - Journal Article DEP - 20151127 PL - England TA - J Cardiothorac Surg JT - Journal of cardiothoracic surgery JID - 101265113 SB - IM MH - Female MH - Follow-Up Studies MH - Hospital Mortality/trends MH - Humans MH - Male MH - Middle Aged MH - Morbidity/trends MH - Pericardiectomy/*methods MH - Pericarditis, Constrictive/epidemiology/*surgery MH - Postoperative Period MH - Retrospective Studies MH - Survival Rate/trends MH - Time Factors MH - Turkey/epidemiology PMC - PMC4662820 EDAT- 2015/11/29 06:00 MHDA- 2016/06/15 06:00 PMCR- 2015/11/27 CRDT- 2015/11/29 06:00 PHST- 2015/03/07 00:00 [received] PHST- 2015/11/18 00:00 [accepted] PHST- 2015/11/29 06:00 [entrez] PHST- 2015/11/29 06:00 [pubmed] PHST- 2016/06/15 06:00 [medline] PHST- 2015/11/27 00:00 [pmc-release] AID - 10.1186/s13019-015-0385-8 [pii] AID - 385 [pii] AID - 10.1186/s13019-015-0385-8 [doi] PST - epublish SO - J Cardiothorac Surg. 2015 Nov 27;10:177. doi: 10.1186/s13019-015-0385-8.