PMID- 26618693
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151202
LR  - 20151201
IS  - 2048-7193 (Print)
IS  - 2048-7193 (Linking)
VI  - 1
IP  - 1
DP  - 2012 Mar
TI  - The California Pertussis Epidemic 2010: A Review of 986 Pediatric Case Reports 
      From San Diego County.
PG  - 47-54
LID - 10.1093/jpids/pis007 [doi]
AB  - BACKGROUND: The California Department of Public Health (CDPH) declared a 
      pertussis epidemic on 23 June 2010. More cases were reported in 2010 (9146) than 
      in any year since 1947. We describe the characteristics of pertussis epidemiology 
      and disease from 986 reported cases in children in San Diego County (population 
      3.2 million). METHODS: Descriptive statistics were abstracted from CDPH pertussis 
      case report forms that were completed by public health nurses investigating 
      reports of positive laboratory results for pertussis and reports of illnesses 
      compatible with pertussis. RESULTS: Of 1144 reported adult and pediatric cases, 
      753 (66%) were confirmed and 391 were probable/suspect. Children aged <19 years 
      comprised 86% of all reported cases in San Diego County; of these, 22% were aged 
      11-18 years, 29% were aged 6-10 years, 27% were aged 1-5 years, and 22% were aged 
      <1 year (with 70% aged <6 months). Case rates were highest in infants aged <6 
      months (651 per 100 000 population). Of those aged >1 year, the highest attack 
      rates were in preschool children aged 1-5 years (114 per 100 000) and elementary 
      school children aged 6-10 years (141 per 100 000). Of 51 children hospitalized, 
      82% were aged <6 months; 2 deaths occurred in these young infants. Paroxysmal 
      cough was noted in over 70% of children in all age groups; post-tussive vomiting 
      occurred in 36% (aged 11-18 years) to 57% (aged <6 months) of children. 
      CONCLUSIONS: Pertussis vaccine efficacy may decrease more rapidly than previously 
      believed, facilitating spread of pertussis in elementary school-aged children. 
      The highest case rates and the only mortality occurred in infants aged <6 months.
CI  - (c) The Author 2012. Published by Oxford University Press on behalf of the 
      Pediatric Infectious Diseases Society. All rights reserved. For Permissions, 
      please e-mail: journals.permissions@oup.com.
FAU - Chan, M H
AU  - Chan MH
AD  - Department of Pediatrics, University of California San Diego School of Medicine.
FAU - Ma, L
AU  - Ma L
AD  - Department of Pediatrics, University of California San Diego School of Medicine.
FAU - Sidelinger, D
AU  - Sidelinger D
AD  - County of San Diego Health and Human Services Agency, Public Health Services 
      Administration.
FAU - Bethel, L
AU  - Bethel L
AD  - County of San Diego Health and Human Services, Epidemiology and Immunization 
      Services Branch.
FAU - Yen, J
AU  - Yen J
AD  - County of San Diego Health and Human Services, Epidemiology and Immunization 
      Services Branch.
FAU - Inveiss, A
AU  - Inveiss A
AD  - Department of Pediatrics, University of California San Diego School of Medicine.
FAU - Sawyer, M H
AU  - Sawyer MH
AD  - Department of Pediatrics, University of California San Diego School of Medicine 
      County of San Diego Health and Human Services, Epidemiology and Immunization 
      Services Branch Rady Children's Hospital San Diego, California.
FAU - Waters-Montijo, K
AU  - Waters-Montijo K
AD  - County of San Diego Health and Human Services, Epidemiology and Immunization 
      Services Branch.
FAU - Johnson, J M
AU  - Johnson JM
AD  - County of San Diego Health and Human Services, Epidemiology and Immunization 
      Services Branch.
FAU - Hicks, L
AU  - Hicks L
AD  - County of San Diego Health and Human Services, Epidemiology and Immunization 
      Services Branch.
FAU - McDonald, E C
AU  - McDonald EC
AD  - County of San Diego Health and Human Services Agency, Public Health Services 
      Administration.
FAU - Ginsberg, M M
AU  - Ginsberg MM
AD  - County of San Diego Health and Human Services, Epidemiology and Immunization 
      Services Branch.
FAU - Bradley, J S
AU  - Bradley JS
AD  - Department of Pediatrics, University of California San Diego School of Medicine 
      Rady Children's Hospital San Diego, California jbradley@rchsd.org.
LA  - eng
PT  - Journal Article
DEP - 20120301
PL  - England
TA  - J Pediatric Infect Dis Soc
JT  - Journal of the Pediatric Infectious Diseases Society
JID - 101586049
EDAT- 2012/03/01 00:00
MHDA- 2012/03/01 00:01
CRDT- 2015/12/01 06:00
PHST- 2011/11/01 00:00 [received]
PHST- 2012/01/12 00:00 [accepted]
PHST- 2015/12/01 06:00 [entrez]
PHST- 2012/03/01 00:00 [pubmed]
PHST- 2012/03/01 00:01 [medline]
AID - pis007 [pii]
AID - 10.1093/jpids/pis007 [doi]
PST - ppublish
SO  - J Pediatric Infect Dis Soc. 2012 Mar;1(1):47-54. doi: 10.1093/jpids/pis007. Epub 
      2012 Mar 1.