PMID- 26626729 OWN - NLM STAT- MEDLINE DCOM- 20160914 LR - 20220316 IS - 1472-6963 (Electronic) IS - 1472-6963 (Linking) VI - 15 DP - 2015 Dec 1 TI - Excess length of stay and economic consequences of adverse events in Dutch hospital patients. PG - 531 LID - 10.1186/s12913-015-1205-5 [doi] LID - 531 AB - BACKGROUND: To investigate the average and extrapolated excess length of stay and direct costs of adverse events (AEs) and preventable AEs in Dutch hospitals, and to evaluate patient characteristics associated with excess length of stay and costs. METHODS: Data of a large retrospective patient record review study on AEs was used. A stratified sample of 20 Dutch hospitals was included. Excess length of stay and costs attributable to AEs and preventable AEs were calculated and extrapolated to a national estimate. The association between patient characteristics and excess length of stay (and costs thereof) attributable to AEs and preventable AEs was investigated through multilevel linear regression analyses. RESULTS: A total of 2975 patient records were included in the analysis, of which 325 experienced one or more AEs. Hospital patients experiencing an AE stayed 5.11 (95% CI 3.91-6.30) more days in hospital and cost euro2600 (95% CI euro1968-euro3232) more compared to those without an AE. There was no significant difference in days and costs between preventable and non-preventable AEs. Extrapolated to a national level, AEs cost more than euro300 million, which was 1.3% of the national hospital care budget. Patients with hospital-acquired infections had a statistically significant longer length of stay compared to the reference group (patients with AEs on the cardiovascular system). CONCLUSIONS: This study showed that AEs lead to substantial excess length of stay and increased costs. Special attention should be paid to patients with AEs due to an hospital-acquired infection. FAU - Hoogervorst-Schilp, Janneke AU - Hoogervorst-Schilp J AD - NIVEL, Netherlands Institute for Health Services Research, PO Box 1568, 3500, BN, Utrecht, The Netherlands. jannekeschilp@hotmail.com. FAU - Langelaan, Maaike AU - Langelaan M AD - NIVEL, Netherlands Institute for Health Services Research, PO Box 1568, 3500, BN, Utrecht, The Netherlands. m.langelaan@nivel.nl. FAU - Spreeuwenberg, Peter AU - Spreeuwenberg P AD - NIVEL, Netherlands Institute for Health Services Research, PO Box 1568, 3500, BN, Utrecht, The Netherlands. p.spreeuwenberg@nivel.nl. FAU - de Bruijne, Martine C AU - de Bruijne MC AD - Department of Public and Occupational Health & EMGO Institute for Health and Care Research, VU University Medical Centre, Van der Boechorststraat 7, 1081, BT, Amsterdam, The Netherlands. mc.debruyne@vumc.nl. FAU - Wagner, Cordula AU - Wagner C AD - NIVEL, Netherlands Institute for Health Services Research, PO Box 1568, 3500, BN, Utrecht, The Netherlands. c.wagner@nivel.nl. AD - Department of Public and Occupational Health & EMGO Institute for Health and Care Research, VU University Medical Centre, Van der Boechorststraat 7, 1081, BT, Amsterdam, The Netherlands. c.wagner@nivel.nl. LA - eng PT - Journal Article DEP - 20151201 PL - England TA - BMC Health Serv Res JT - BMC health services research JID - 101088677 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Costs and Cost Analysis MH - Female MH - *Hospital Costs MH - Humans MH - Infant MH - *Inpatients MH - Length of Stay/*economics MH - Linear Models MH - Male MH - Medical Audit MH - *Medical Errors MH - Middle Aged MH - Netherlands MH - Retrospective Studies MH - Young Adult PMC - PMC4667531 EDAT- 2015/12/03 06:00 MHDA- 2016/09/15 06:00 PMCR- 2015/12/01 CRDT- 2015/12/03 06:00 PHST- 2015/04/10 00:00 [received] PHST- 2015/11/30 00:00 [accepted] PHST- 2015/12/03 06:00 [entrez] PHST- 2015/12/03 06:00 [pubmed] PHST- 2016/09/15 06:00 [medline] PHST- 2015/12/01 00:00 [pmc-release] AID - 10.1186/s12913-015-1205-5 [pii] AID - 1205 [pii] AID - 10.1186/s12913-015-1205-5 [doi] PST - epublish SO - BMC Health Serv Res. 2015 Dec 1;15:531. doi: 10.1186/s12913-015-1205-5.