PMID- 26631137
OWN - NLM
STAT- MEDLINE
DCOM- 20170328
LR  - 20240109
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 254
IP  - 8
DP  - 2016 Aug
TI  - Interpretation of fundus autofluorescence changes in choriocapillaritis: a 
      multi-modality imaging study.
PG  - 1473-1479
LID - 10.1007/s00417-015-3205-x [doi]
AB  - PURPOSE: We aimed to describe imaging findings in primary inflammatory 
      choriocapillaropathies (PICCPs) after a photobleaching process. METHODS: 2Images 
      from six consecutive cases of patients affected by PICCPs (four with multiple 
      evanescent white dot syndrome and two with multifocal choroiditis) were reviewed. 
      Patients underwent fundus autofluorescence (FAF), fluorescein angiography (FA), 
      indocyanine green angiography (ICGA), and spectral-domain optical coherence 
      tomography (SD-OCT) by means of the Spectralis HRA (Heidelberg Engineering, 
      Heidelberg, Germany). FAF images were acquired at the beginning of the 
      examination in partially dark-adapted conditions followed by light adapted 
      conditions. RESULTS: During the active phase of the diseases, all patients showed 
      areas of increased FAF that became isoautofluorescent after photobleaching. 
      Simultaneously with increased FAF, the ICGA showed typical hypofluorescent dark 
      areas that were more evident in the late phase. SD-OCT showed disruptions in the 
      hyper-reflective band at the ellipsoid zone. CONCLUSIONS: FAF and SD-OCT are 
      complementary imaging techniques that show alterations in the outer retina of 
      patients affected by PICCPs.
FAU - Mantovani, Alessandro
AU  - Mantovani A
AD  - Ophthalmology Unit, Ospedale Valduce, Como, Italy.
FAU - Giani, Andrea
AU  - Giani A
AD  - Eye Clinic Department of Clinical Science "Luigi Sacco", Luigi Sacco Hospital 
      University of Milan, via G.B. Grassi, 74 - 20157, Milan, Italy.
FAU - Herbort, Carl P Jr
AU  - Herbort CP Jr
AD  - Retinal and Inflammatory Eye Diseases, Centre for Ophthalmic Specialised Care & 
      University of Lausanne, Lausanne, Switzerland.
FAU - Staurenghi, Giovanni
AU  - Staurenghi G
AD  - Eye Clinic Department of Clinical Science "Luigi Sacco", Luigi Sacco Hospital 
      University of Milan, via G.B. Grassi, 74 - 20157, Milan, Italy. 
      giovanni.staurenghi@unimi.it.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20151203
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Adult
MH  - Aged
MH  - Choroiditis/*diagnosis
MH  - Female
MH  - Fluorescein Angiography/*methods
MH  - Fundus Oculi
MH  - Humans
MH  - Image Interpretation, Computer-Assisted/*methods
MH  - Male
MH  - Middle Aged
MH  - Multifocal Choroiditis
MH  - Multimodal Imaging/*methods
MH  - Retinal Pigment Epithelium/*diagnostic imaging
MH  - Tomography, Optical Coherence/methods
MH  - Visual Acuity
MH  - Young Adult
OTO - NOTNLM
OT  - Fundus autofluorescence
OT  - Inflammatory choriocapillaropathies
OT  - Photobleaching
OT  - Spectral domain-optical coherence tomography
EDAT- 2015/12/04 06:00
MHDA- 2017/03/30 06:00
CRDT- 2015/12/04 06:00
PHST- 2015/08/09 00:00 [received]
PHST- 2015/10/20 00:00 [accepted]
PHST- 2015/10/15 00:00 [revised]
PHST- 2015/12/04 06:00 [entrez]
PHST- 2015/12/04 06:00 [pubmed]
PHST- 2017/03/30 06:00 [medline]
AID - 10.1007/s00417-015-3205-x [pii]
AID - 10.1007/s00417-015-3205-x [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2016 Aug;254(8):1473-1479. doi: 
      10.1007/s00417-015-3205-x. Epub 2015 Dec 3.