PMID- 26634215
OWN - NLM
STAT- MEDLINE
DCOM- 20161005
LR  - 20190723
IS  - 2314-6753 (Electronic)
IS  - 2314-6745 (Print)
VI  - 2016
DP  - 2016
TI  - New Methods in Exploring Old Topics: Case Studying Brittle Diabetes in the Family 
      Context.
PG  - 6437452
LID - 10.1155/2016/6437452 [doi]
LID - 6437452
AB  - BACKGROUND: In questing for a more refined quantitative research approach, we 
      revisited vector autoregressive (VAR) modeling for the analysis of time series 
      data in the context of the so far poorly explored concept of family dynamics 
      surrounding instable diabetes type 1 (or brittle diabetes). METHOD: We adopted a 
      new approach to VAR analysis from econometrics referred to as the optimized 
      multivariate lag selection process and applied it to a set of raw data previously 
      analyzed through standard approaches. RESULTS: We illustrated recurring 
      psychosomatic circles of cause and effect relationships between emotional and 
      somatic parameters surrounding glycemic control of the child's diabetes and the 
      affective states of all family members. CONCLUSION: The optimized multivariate 
      lag selection process allowed for more specific, dynamic, and statistically 
      reliable results (increasing R(2) tenfold in explaining glycemic variability), 
      which were derived from a larger window of past explanatory variables (lags). 
      Such highly quantitative versus historic more qualitative approaches to case 
      study analysis of psychosomatics surrounding diabetes in adolescents were 
      reflected critically.
FAU - Gunther, Moritz Philipp
AU  - Gunther MP
AD  - Psychoanalytic Family Therapy, Center of Child and Adolescent Medicine, 
      Justus-Liebig-University, Feulgenstrasse 10-12, 35392 Giessen, Germany.
FAU - Winker, Peter
AU  - Winker P
AD  - Department of Economics, Justus-Liebig-University Giessen, Licher Strasse 64, 
      35394 Giessen, Germany.
FAU - Wudy, Stefan A
AU  - Wudy SA
AD  - Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, 
      Justus-Liebig-University, Feulgenstrasse 10-12, 35392 Giessen, Germany.
FAU - Brosig, Burkhard
AU  - Brosig B
AD  - Psychoanalytic Family Therapy, Center of Child and Adolescent Medicine, 
      Justus-Liebig-University, Feulgenstrasse 10-12, 35392 Giessen, Germany.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20151108
PL  - England
TA  - J Diabetes Res
JT  - Journal of diabetes research
JID - 101605237
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adolescent
MH  - *Blood Glucose
MH  - Diabetes Mellitus, Type 1/blood/*diagnosis/*genetics
MH  - Humans
MH  - Male
PMC - PMC4655046
EDAT- 2015/12/04 06:00
MHDA- 2016/10/07 06:00
PMCR- 2015/11/08
CRDT- 2015/12/04 06:00
PHST- 2014/10/31 00:00 [received]
PHST- 2015/03/07 00:00 [accepted]
PHST- 2015/12/04 06:00 [entrez]
PHST- 2015/12/04 06:00 [pubmed]
PHST- 2016/10/07 06:00 [medline]
PHST- 2015/11/08 00:00 [pmc-release]
AID - 10.1155/2016/6437452 [doi]
PST - ppublish
SO  - J Diabetes Res. 2016;2016:6437452. doi: 10.1155/2016/6437452. Epub 2015 Nov 8.