PMID- 26634227
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240324
VI  - 1
IP  - 1
DP  - 2015
TI  - Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome.
LID - 1104 [pii]
AB  - INTRODUCTION: Identification of risk factors for obstructive sleep apnea (OSA) is 
      important to enable comprehensive intervention to reduce OSA-related 
      cardiovascular disease (CVD). The metabolic syndrome outcome study (MetSO) 
      provides a unique opportunity to address these factors. This study investigated 
      risk of OSA among blacks with metabolic syndrome. METHODS: The present study 
      utilized data from MetSO, an NIH-funded cohort study of blacks with metabolic 
      syndrome. A total of 1,035 patients provided data for the analysis. These 
      included sociodemographic factors, health risks, and medical history. 
      Physician-diagnosed conditions were obtained using an electronic medical record 
      system (Allscripts, Sunrise Enterprise). Patients were diagnosed with metabolic 
      syndrome using criteria articulated in the joint interim statement for 
      harmonizing the metabolic syndrome. Patients with a score >/=6 on the Apnea Risk 
      Evaluation System (ARES) questionnaire were considered at risk for OSA. Obesity 
      is defined by body mass index (BMI >/= 30 kg/m(2)). RESULTS: Of the 1,035 patients 
      screened in the MetSO cohort, 48.9% were at high risk for OSA. Using 
      multivariate-adjusted logistic regression analysis, we observed that obesity was 
      the strongest predictor of OSA risk (OR=1.59, 95%CI=1.24-2.04, p<0.0001). This 
      finding remained significant even after adjustment for known covariates including 
      blood pressure, low-density lipoprotein, high-density lipoprotein, and glucose 
      levels (OR=1.44, 95%CI=1.11-1.86, p<0.001). CONCLUSION: Blacks in the MetSO 
      cohort are at greater OSA risk, relative to the adult population in developed 
      countries. Consistent with previous observations, obesity proved the strongest 
      independent predictor of OSA risk among blacks with metabolic syndrome.
FAU - Rogers, A
AU  - Rogers A
AD  - Center for Healthful Behavior Change (CHBC), Division of Health and Behavior, 
      Department of Population Health, New York University Medical Center, New York, 
      USA.
FAU - Ravenell, J
AU  - Ravenell J
AD  - Department of Family Medicine, SUNY Downstate Medical Center, New York, USA.
FAU - Donat, M
AU  - Donat M
AD  - Division of Endocrinology, Department of Medicine, State University of New 
      York-Downstate Medical Center, Brooklyn, USA.
FAU - Sexias, A
AU  - Sexias A
AD  - Department of Emergency Medicine, Hackensack UMC, Hackensack, NJ, USA.
FAU - Ogedegbe, C
AU  - Ogedegbe C
FAU - McFarlane, S I
AU  - McFarlane SI
FAU - Jean-Louis, G
AU  - Jean-Louis G
LA  - eng
GR  - K01 HL135452/HL/NHLBI NIH HHS/United States
GR  - U54 NS081765/NS/NINDS NIH HHS/United States
GR  - R01 MD007716/MD/NIMHD NIH HHS/United States
GR  - R01 MD004113/MD/NIMHD NIH HHS/United States
GR  - R01 HL095799/HL/NHLBI NIH HHS/United States
PT  - Journal Article
DEP - 20150527
PL  - United States
TA  - J Obes Overweight
JT  - Journal of Obesity and Overweight
JID - 101653762
PMC - PMC4664188
MID - NIHMS724947
OTO - NOTNLM
OT  - Blacks
OT  - Metabolic syndrome
OT  - Obesity
OT  - Obstructive sleep apnea
EDAT- 2015/12/04 06:00
MHDA- 2015/12/04 06:01
PMCR- 2015/11/30
CRDT- 2015/12/04 06:00
PHST- 2015/12/04 06:00 [entrez]
PHST- 2015/12/04 06:00 [pubmed]
PHST- 2015/12/04 06:01 [medline]
PHST- 2015/11/30 00:00 [pmc-release]
AID - 1104 [pii]
PST - ppublish
SO  - J Obes Overweight. 2015;1(1):1104. Epub 2015 May 27.