PMID- 26635041
OWN - NLM
STAT- MEDLINE
DCOM- 20160919
LR  - 20190606
IS  - 1643-3750 (Electronic)
IS  - 1234-1010 (Print)
IS  - 1234-1010 (Linking)
VI  - 21
DP  - 2015 Dec 4
TI  - Short-Term and Long-Term Survival After Revascularization with or without Mitral 
      Valve Surgery of Patients with Ischemic Mitral Valve Regurgitation: A 
      Meta-Analysis.
PG  - 3784-91
AB  - BACKGROUND There is no consensus on whether mitral valve repair or replacement 
      (MVRR) must be performed to treat ischemic mitral regurgitation (MVR) after 
      myocardial infarction. Our objective in this study was to investigate the 
      efficacy of coronary artery bypass grafting (CABG) combined with or without MVRR 
      for the ischemic MVR. MATERIAL AND METHODS An article search was performed in 
      OvidSP, PubMed, Cochrane Library, and Embase. In these articles, researchers 
      compared the efficacy of CABG with or without MVRR in treating patients with 
      ischemic MVR after acute coronary syndrome (ACS). We performed a meta-analysis to 
      compare the differences in the short-term and long-term survival rates of 
      patients treated with CABG only and those treated with both CABG and MVRR. 
      Secondary outcomes were compared with the preoperative and postoperative degree 
      of MVR, left ventricular end-systolic volume (LVESV), left ventricular ejection 
      fraction (LVEF), and New York Heart Association (NYHA) class. RESULTS Out of the 
      1183 studies, we selected only 5 articles. A total of 3120 patients were 
      enrolled; the CABG and MVRR group included 575 patients, while the CABG only 
      group included 2545 patients. Long-term survival was higher in the CABG only 
      group (hazard ratio [HR], 1.34; 95% confidence interval [CI] 1.15-1.58, P=0.003). 
      Hospital mortality was similar in both the groups (odds ratio [OR], 2.54; 95% CI, 
      0.65-9.95; P=0.18). No differences were found in the degree of residual MVR, the 
      mean of LVESV, LVEF, or NYHA class. CONCLUSIONS In patients with ischemic MVR, 
      the short-term survival rate was similar in both groups. Moreover, there was no 
      significant improvement in the long-term survival rates of patients treated with 
      both CAG and MVRR.
FAU - Zhang, Hua
AU  - Zhang H
AD  - Southern Medical University, Guangzhou, Guangdong, China (mainland).
FAU - Liu, Yili
AU  - Liu Y
AD  - Southern Medical University, Guangzhou, Guangdong, China (mainland).
FAU - Qiu, Shaodong
AU  - Qiu S
AD  - Department of Medical Ultrasound, The Second Affiliated Hospital of Guangzhou 
      Medical University, Guangzhou, Guangdong, China (mainland).
FAU - Liang, Weixiang
AU  - Liang W
AD  - Department of Medical Ultrasound, The Third Affiliated Hospital of Guangzhou 
      Medical University, Guangzhou, Guangdong, China (mainland).
FAU - Jiang, Lan
AU  - Jiang L
AD  - Department of Medical Ultrasound, The Third Affiliated Hospital of Guangzhou 
      Medical University, Guangzhou, Guangdong, China (mainland).
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
DEP - 20151204
PL  - United States
TA  - Med Sci Monit
JT  - Medical science monitor : international medical journal of experimental and 
      clinical research
JID - 9609063
SB  - IM
MH  - Aged
MH  - *Coronary Artery Bypass
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/*physiopathology/surgery
MH  - Myocardial Ischemia/*physiopathology/surgery
PMC - PMC4672719
EDAT- 2015/12/05 06:00
MHDA- 2016/09/20 06:00
PMCR- 2015/12/04
CRDT- 2015/12/05 06:00
PHST- 2015/12/05 06:00 [entrez]
PHST- 2015/12/05 06:00 [pubmed]
PHST- 2016/09/20 06:00 [medline]
PHST- 2015/12/04 00:00 [pmc-release]
AID - 895954 [pii]
AID - 10.12659/msm.895954 [doi]
PST - epublish
SO  - Med Sci Monit. 2015 Dec 4;21:3784-91. doi: 10.12659/msm.895954.