PMID- 26635335
OWN - NLM
STAT- MEDLINE
DCOM- 20180827
LR  - 20180827
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Linking)
VI  - 67
IP  - 8
DP  - 2016 Sep
TI  - Structured Home-Based Exercise Versus Invasive Treatment: A Mission Impossible? A 
      Pilot Randomized Study in Elderly Patients With Intermittent Claudication.
PG  - 772-80
LID - 10.1177/0003319715618481 [doi]
AB  - We compared the effects of an original structured home-based exercise program and 
      revascularization in elderly patients with peripheral arterial disease over a 
      4-month period. Twenty-seven participants (n = 21; age = 68 +/- 7 years) with 
      moderate to severe claudication were randomized into (1) a test in-train out 
      group (Ti-To; n = 18) that performed a home-based walking program prescribed and 
      controlled at the hospital or (2) a revascularization group (Rev; n = 9) that 
      underwent an endovascular and/or surgical procedure. The primary end point was 
      quality of life as evaluated by the physical component summary (PCS) score of the 
      Medical Outcomes Study Short Form 36 questionnaire. Secondary outcome measures 
      included initial claudication distance (ICD) and absolute claudication distance 
      (ACD), 6-minute walk distance (6MWD) and pain-free walk distance (PFWD), 
      ankle-brachial index (ABI), and cost per walking meter gained. The PCS score 
      significantly increased for both treatments at follow-up without a significant 
      intergroup difference, as did ICD, ACD, and PFWD. The 6MWD and ABI significantly 
      improved in the Rev group, and the Ti-To group exhibited a markedly lower cost 
      per meter gained. The comparable effects of the 2 treatments need to be confirmed 
      in a larger, randomized controlled trial.
CI  - (c) The Author(s) 2015.
FAU - Lamberti, Nicola
AU  - Lamberti N
AD  - Department of Biomedical Sciences and Surgical Specialties, Section of Sport 
      Sciences, University of Ferrara, Ferrara, Italy.
FAU - Malagoni, Anna Maria
AU  - Malagoni AM
AD  - Unit of Translational Surgery, Hospital University of Ferrara, Ferrara, Italy 
      mlgnmr@unife.it.
FAU - Ficarra, Valentina
AU  - Ficarra V
AD  - Unit of Vascular and Endovascular Surgery, Hospital University of Ferrara, 
      Ferrara, Italy.
FAU - Basaglia, Nino
AU  - Basaglia N
AD  - Department of Rehabilitation Medicine, Hospital University, Ferrara, Italy.
FAU - Manfredini, Roberto
AU  - Manfredini R
AD  - Clinica Medica, Department of Medical Sciences, University of Ferrara, Ferrara, 
      Italy.
FAU - Zamboni, Paolo
AU  - Zamboni P
AD  - Unit of Translational Surgery, Hospital University of Ferrara, Ferrara, Italy.
FAU - Mascoli, Francesco
AU  - Mascoli F
AD  - Unit of Vascular and Endovascular Surgery, Hospital University of Ferrara, 
      Ferrara, Italy.
FAU - Manfredini, Fabio
AU  - Manfredini F
AD  - Department of Biomedical Sciences and Surgical Specialties, Section of Sport 
      Sciences, University of Ferrara, Ferrara, Italy Department of Rehabilitation 
      Medicine, Hospital University, Ferrara, Italy.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20151203
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
SB  - IM
MH  - Aged
MH  - Cost-Benefit Analysis
MH  - *Endovascular Procedures/adverse effects/economics
MH  - Exercise Therapy/adverse effects/economics/*methods
MH  - Exercise Tolerance
MH  - Female
MH  - Health Care Costs
MH  - *Home Care Services, Hospital-Based/economics
MH  - Humans
MH  - Intermittent Claudication/diagnosis/economics/physiopathology/*therapy
MH  - Italy
MH  - Male
MH  - Middle Aged
MH  - Peripheral Arterial Disease/diagnosis/economics/physiopathology/*therapy
MH  - Pilot Projects
MH  - Quality of Life
MH  - Recovery of Function
MH  - Surveys and Questionnaires
MH  - Time Factors
MH  - Treatment Outcome
MH  - *Vascular Surgical Procedures/adverse effects/economics
MH  - Walk Test
MH  - Walking
OTO - NOTNLM
OT  - endovascular procedures
OT  - exercise
OT  - intermittent claudication
OT  - peripheral arterial disease
OT  - quality of life
OT  - vascular surgical procedures
EDAT- 2015/12/05 06:00
MHDA- 2018/08/28 06:00
CRDT- 2015/12/05 06:00
PHST- 2015/12/05 06:00 [entrez]
PHST- 2015/12/05 06:00 [pubmed]
PHST- 2018/08/28 06:00 [medline]
AID - 0003319715618481 [pii]
AID - 10.1177/0003319715618481 [doi]
PST - ppublish
SO  - Angiology. 2016 Sep;67(8):772-80. doi: 10.1177/0003319715618481. Epub 2015 Dec 3.