PMID- 26635573
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151204
LR  - 20200929
IS  - 1662-5161 (Print)
IS  - 1662-5161 (Electronic)
IS  - 1662-5161 (Linking)
VI  - 9
DP  - 2015
TI  - The Neural Correlates of Optimistic and Depressive Tendencies of Self-Evaluations 
      and Resting-State Default Mode Network.
PG  - 618
LID - 10.3389/fnhum.2015.00618 [doi]
LID - 618
AB  - Unrealistic optimism is common among people making self-evaluations while reduced 
      optimism has been linked to increased depressive symptoms. Given the importance 
      of optimism for adaptive functioning, surprisingly little is known about resting 
      brain states underlying optimistic and depressive tendencies. In the current 
      study, two resting-state indices were used to examine neural correlates of the 
      default mode network (DMN) associated with optimistic and depressive 
      self-evaluation tendencies in a non-clinical young adult sample (N = 49). The 
      analysis was constrained due to the self-referential nature of the DMN. Across 
      different indices, bilateral superior frontal gyri of the dorsolateral prefrontal 
      cortex (DLPFC) and bilateral superior medial frontal gyri of the dorsal medial 
      prefrontal cortex (DMPFC) played a key role in maintaining spontaneous optimistic 
      self-evaluative tendencies. Conversely, decreased activity in the DLPFC and 
      bilateral medial orbitofrontal cortices (OFC) were related to accentuated 
      depressive symptoms. Together, results highlight the pivotal roles of the DLPFC 
      and DMPFC in mediating valences of self-referential content.
FAU - Wu, Jinfeng
AU  - Wu J
AD  - Key Laboratory of Cognition and Personality, Faculty of Psychology, Southwest 
      University Chongqing, China.
FAU - Dong, Debo
AU  - Dong D
AD  - School of Life Science and Technology, University of Electronic Science and 
      Technology of China Chengdu, China.
FAU - Jackson, Todd
AU  - Jackson T
AD  - Key Laboratory of Cognition and Personality, Faculty of Psychology, Southwest 
      University Chongqing, China.
FAU - Wang, Yu
AU  - Wang Y
AD  - Key Laboratory of Cognition and Personality, Faculty of Psychology, Southwest 
      University Chongqing, China.
FAU - Huang, Junfeng
AU  - Huang J
AD  - Key Laboratory of Cognition and Personality, Faculty of Psychology, Southwest 
      University Chongqing, China.
FAU - Chen, Hong
AU  - Chen H
AD  - Key Laboratory of Cognition and Personality, Faculty of Psychology, Southwest 
      University Chongqing, China.
LA  - eng
PT  - Journal Article
DEP - 20151118
PL  - Switzerland
TA  - Front Hum Neurosci
JT  - Frontiers in human neuroscience
JID - 101477954
PMC - PMC4649049
OTO - NOTNLM
OT  - default mode network
OT  - depression
OT  - optimism
OT  - resting-state
OT  - self-evaluation
EDAT- 2015/12/05 06:00
MHDA- 2015/12/05 06:01
PMCR- 2015/01/01
CRDT- 2015/12/05 06:00
PHST- 2015/07/15 00:00 [received]
PHST- 2015/10/26 00:00 [accepted]
PHST- 2015/12/05 06:00 [entrez]
PHST- 2015/12/05 06:00 [pubmed]
PHST- 2015/12/05 06:01 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
AID - 10.3389/fnhum.2015.00618 [doi]
PST - epublish
SO  - Front Hum Neurosci. 2015 Nov 18;9:618. doi: 10.3389/fnhum.2015.00618. eCollection 
      2015.