PMID- 26638759
OWN - NLM
STAT- MEDLINE
DCOM- 20160729
LR  - 20221207
IS  - 1873-6246 (Electronic)
IS  - 0301-0511 (Linking)
VI  - 113
DP  - 2016 Jan
TI  - Subgroup differences in the lexical tone mismatch negativity (MMN) among Mandarin 
      speakers with congenital amusia.
PG  - 59-67
LID - S0301-0511(15)30086-7 [pii]
LID - 10.1016/j.biopsycho.2015.11.010 [doi]
AB  - The association/dissociation of pitch processing between music and language is a 
      long lasting debate. We examined this music-language relationship by 
      investigating to what extent pitch deficits in these two domains were 
      dissociable. We focused on a special neurodevelopmental pitch disorder - 
      congenital amusia, which primarily affects musical pitch processing. Recent 
      research has also revealed lexical tone deficits in speech among amusics. 
      Approximately one-third of Mandarin amusics exhibits behavioural difficulties in 
      lexical tone perception, which is known as tone agnosia. Using mismatch 
      negativities (MMNs), our current work probed lexical tone encoding at the 
      pre-attentive level among the Mandarin amusics with (tone agnosics) and without 
      (pure amusics) behavioural lexical tone deficits compared with age- and 
      IQ-matched controls. Relative to the controls and the pure amusics, the tone 
      agnosics exhibited reduced MMNs specifically in response to lexical tone changes. 
      Their tone-consonant MMNs were intact and similar to those of the other two 
      groups. Moreover, the tone MMN reduction over the left hemisphere was tightly 
      linked to behavioural insensitivity to lexical tone changes. The current study 
      thus provides the first psychophysiological evidence of subgroup differences in 
      lexical tone processing among Mandarin amusics and links amusics' behavioural 
      tone deficits to impaired pre-attentive tone processing. Despite the overall 
      music pitch deficits, the subgroup differences in lexical tone processing in 
      Mandarin-speaking amusics suggest dissociation of pitch deficits between music 
      and speech.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Nan, Yun
AU  - Nan Y
AD  - State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern 
      Institute for Brain Research, Beijing Normal University, Beijing, China. 
      Electronic address: nany@bnu.edu.cn.
FAU - Huang, Wan-ting
AU  - Huang WT
AD  - State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern 
      Institute for Brain Research, Beijing Normal University, Beijing, China.
FAU - Wang, Wen-jing
AU  - Wang WJ
AD  - State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern 
      Institute for Brain Research, Beijing Normal University, Beijing, China.
FAU - Liu, Chang
AU  - Liu C
AD  - Department of Communication Sciences and Disorders, The University of Texas at 
      Austin, Austin, TX, USA.
FAU - Dong, Qi
AU  - Dong Q
AD  - State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern 
      Institute for Brain Research, Beijing Normal University, Beijing, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20151127
PL  - Netherlands
TA  - Biol Psychol
JT  - Biological psychology
JID - 0375566
RN  - Tune Deafness
SB  - IM
MH  - Acoustic Stimulation
MH  - Adolescent
MH  - Adult
MH  - Agnosia/*psychology
MH  - Asian People
MH  - Auditory Perceptual Disorders/*psychology
MH  - Electroencephalography
MH  - Female
MH  - Functional Laterality
MH  - Humans
MH  - *Language
MH  - Male
MH  - Music/*psychology
MH  - Pitch Perception
MH  - Reaction Time/physiology
MH  - Speech Perception
MH  - Young Adult
OTO - NOTNLM
OT  - Congenital amusia
OT  - Lexical tone
OT  - Mismatch negativity
OT  - Musical pitch
EDAT- 2015/12/08 06:00
MHDA- 2016/07/30 06:00
CRDT- 2015/12/08 06:00
PHST- 2015/04/10 00:00 [received]
PHST- 2015/10/20 00:00 [revised]
PHST- 2015/11/24 00:00 [accepted]
PHST- 2015/12/08 06:00 [entrez]
PHST- 2015/12/08 06:00 [pubmed]
PHST- 2016/07/30 06:00 [medline]
AID - S0301-0511(15)30086-7 [pii]
AID - 10.1016/j.biopsycho.2015.11.010 [doi]
PST - ppublish
SO  - Biol Psychol. 2016 Jan;113:59-67. doi: 10.1016/j.biopsycho.2015.11.010. Epub 2015 
      Nov 27.