PMID- 26639572 OWN - NLM STAT- MEDLINE DCOM- 20161010 LR - 20190109 IS - 2045-2322 (Electronic) IS - 2045-2322 (Linking) VI - 5 DP - 2015 Dec 7 TI - Scalable lithography from Natural DNA Patterns via polyacrylamide gel. PG - 17872 LID - 10.1038/srep17872 [doi] LID - 17872 AB - A facile strategy for fabricating scalable stamps has been developed using cross-linked polyacrylamide gel (PAMG) that controllably and precisely shrinks and swells with water content. Aligned patterns of natural DNA molecules were prepared by evaporative self-assembly on a PMMA substrate, and were transferred to unsaturated polyester resin (UPR) to form a negative replica. The negative was used to pattern the linear structures onto the surface of water-swollen PAMG, and the pattern sizes on the PAMG stamp were customized by adjusting the water content of the PAMG. As a result, consistent reproduction of DNA patterns could be achieved with feature sizes that can be controlled over the range of 40%-200% of the original pattern dimensions. This methodology is novel and may pave a new avenue for manufacturing stamp-based functional nanostructures in a simple and cost-effective manner on a large scale. FAU - Qu, JieHao AU - Qu J AD - State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China. AD - Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Ministry of Education, College of Materials and Textile, Zhejiang Sci-Tech University, Hangzhou 310018, P.R. China. FAU - Hou, XianLiang AU - Hou X AD - State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China. FAU - Fan, WanChao AU - Fan W AD - Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Ministry of Education, College of Materials and Textile, Zhejiang Sci-Tech University, Hangzhou 310018, P.R. China. FAU - Xi, GuangHui AU - Xi G AD - Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Ministry of Education, College of Materials and Textile, Zhejiang Sci-Tech University, Hangzhou 310018, P.R. China. FAU - Diao, HongYan AU - Diao H AD - State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China. FAU - Liu, XiangDon AU - Liu X AD - Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Ministry of Education, College of Materials and Textile, Zhejiang Sci-Tech University, Hangzhou 310018, P.R. China. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20151207 PL - England TA - Sci Rep JT - Scientific reports JID - 101563288 RN - 0 (Acrylic Resins) RN - 0 (Polyesters) RN - 0 (polyacrylamide gels) RN - 059QF0KO0R (Water) RN - 9007-49-2 (DNA) RN - 9011-14-7 (Polymethyl Methacrylate) SB - IM MH - Acrylic Resins/*chemistry MH - Animals MH - DNA/*chemistry MH - Imaging, Three-Dimensional MH - Microscopy, Atomic Force MH - Optical Phenomena MH - Polyesters/chemistry MH - Polymethyl Methacrylate/chemistry MH - Printing/*methods MH - Salmon MH - Water/chemistry PMC - PMC4671135 EDAT- 2015/12/08 06:00 MHDA- 2016/10/11 06:00 PMCR- 2015/12/07 CRDT- 2015/12/08 06:00 PHST- 2015/08/20 00:00 [received] PHST- 2015/11/05 00:00 [accepted] PHST- 2015/12/08 06:00 [entrez] PHST- 2015/12/08 06:00 [pubmed] PHST- 2016/10/11 06:00 [medline] PHST- 2015/12/07 00:00 [pmc-release] AID - srep17872 [pii] AID - 10.1038/srep17872 [doi] PST - epublish SO - Sci Rep. 2015 Dec 7;5:17872. doi: 10.1038/srep17872.